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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD6
All Species:
7.27
Human Site:
T49
Identified Species:
16
UniProt:
Q8TBK2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBK2
NP_001153777
473
53020
T49
E
R
A
G
G
R
R
T
R
G
G
A
R
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102146
481
54024
T49
E
R
A
G
G
R
R
T
R
G
G
A
R
A
A
Dog
Lupus familis
XP_544379
453
51445
K43
V
G
L
E
L
I
P
K
V
T
V
S
R
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWY3
473
52942
F49
E
G
D
A
V
A
G
F
L
R
W
C
R
R
V
Rat
Rattus norvegicus
NP_001099637
474
53343
F50
E
S
D
A
V
A
G
F
L
R
W
C
T
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507526
513
58286
F83
G
A
G
P
L
P
A
F
L
R
W
C
R
R
A
Chicken
Gallus gallus
Q5ZK17
447
50631
S45
I
S
R
R
G
T
V
S
G
Y
G
L
L
A
A
Frog
Xenopus laevis
Q6INM2
455
52340
V40
G
L
E
L
N
P
K
V
Y
I
S
T
E
G
T
Zebra Danio
Brachydanio rerio
Q803K4
460
52989
L40
T
L
S
D
K
V
Y
L
S
K
E
G
T
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181160
466
53174
Q41
M
F
L
S
W
C
E
Q
E
G
I
I
Q
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12504
494
57270
T44
Q
G
R
A
V
V
A
T
Q
K
I
K
K
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.8
83.9
N.A.
77.1
77.6
N.A.
61.4
64.4
56.2
49
N.A.
N.A.
N.A.
N.A.
40.8
Protein Similarity:
100
N.A.
95.8
86.8
N.A.
83.3
82.9
N.A.
71.1
76.1
71.2
67.8
N.A.
N.A.
N.A.
N.A.
57.7
P-Site Identity:
100
N.A.
100
6.6
N.A.
13.3
6.6
N.A.
13.3
26.6
0
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
100
13.3
N.A.
13.3
6.6
N.A.
13.3
33.3
6.6
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
28
0
19
19
0
0
0
0
19
0
37
46
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
28
0
0
0
% C
% Asp:
0
0
19
10
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
37
0
10
10
0
0
10
0
10
0
10
0
10
0
10
% E
% Phe:
0
10
0
0
0
0
0
28
0
0
0
0
0
0
0
% F
% Gly:
19
28
10
19
28
0
19
0
10
28
28
10
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
10
19
10
0
0
0
% I
% Lys:
0
0
0
0
10
0
10
10
0
19
0
10
10
0
0
% K
% Leu:
0
19
19
10
19
0
0
10
28
0
0
10
10
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
10
0
19
10
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
10
10
0
0
0
10
10
0
% Q
% Arg:
0
19
19
10
0
19
19
0
19
28
0
0
46
28
0
% R
% Ser:
0
19
10
10
0
0
0
10
10
0
10
10
0
0
10
% S
% Thr:
10
0
0
0
0
10
0
28
0
10
0
10
19
0
10
% T
% Val:
10
0
0
0
28
19
10
10
10
0
10
0
0
0
19
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
28
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _