Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SETD6 All Species: 18.79
Human Site: Y143 Identified Species: 41.33
UniProt: Q8TBK2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBK2 NP_001153777 473 53020 Y143 P A S R W R P Y F A L W P E L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001102146 481 54024 Y144 P A S R W R P Y F A L W P E L
Dog Lupus familis XP_544379 453 51445 H135 P E L G R L E H P M F W P E E
Cat Felis silvestris
Mouse Mus musculus Q9CWY3 473 52942 Y143 P A S P W S P Y F A L W P E L
Rat Rattus norvegicus NP_001099637 474 53343 Y144 P A S P W S P Y F A L W P E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507526 513 58286 Y183 S D S P W H H Y F S L W P D L
Chicken Gallus gallus Q5ZK17 447 50631 E134 H P M F W P E E E R V R L L Q
Frog Xenopus laevis Q6INM2 455 52340 M131 P E L D P P D M P M F W S E E
Zebra Danio Brachydanio rerio Q803K4 460 52989 Q129 P D F R T L D Q P M F W S E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181160 466 53174 Y131 R S S R W R P Y L D L F P D Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12504 494 57270 L133 W D D N E L Q L L K P S L V L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.8 83.9 N.A. 77.1 77.6 N.A. 61.4 64.4 56.2 49 N.A. N.A. N.A. N.A. 40.8
Protein Similarity: 100 N.A. 95.8 86.8 N.A. 83.3 82.9 N.A. 71.1 76.1 71.2 67.8 N.A. N.A. N.A. N.A. 57.7
P-Site Identity: 100 N.A. 100 26.6 N.A. 86.6 86.6 N.A. 53.3 6.6 20 26.6 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 N.A. 100 33.3 N.A. 86.6 86.6 N.A. 66.6 13.3 20 26.6 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 37 0 0 0 0 0 0 0 37 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 28 10 10 0 0 19 0 0 10 0 0 0 19 0 % D
% Glu: 0 19 0 0 10 0 19 10 10 0 0 0 0 64 28 % E
% Phe: 0 0 10 10 0 0 0 0 46 0 28 10 0 0 0 % F
% Gly: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 10 0 0 0 0 10 10 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 0 0 19 0 0 28 0 10 19 0 55 0 19 10 55 % L
% Met: 0 0 10 0 0 0 0 10 0 28 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 64 10 0 28 10 19 46 0 28 0 10 0 64 0 0 % P
% Gln: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 10 % Q
% Arg: 10 0 0 37 10 28 0 0 0 10 0 10 0 0 0 % R
% Ser: 10 10 55 0 0 19 0 0 0 10 0 10 19 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % V
% Trp: 10 0 0 0 64 0 0 0 0 0 0 73 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 55 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _