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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SETD6 All Species: 28.48
Human Site: Y303 Identified Species: 62.67
UniProt: Q8TBK2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBK2 NP_001153777 473 53020 Y303 M Y G F V E P Y P D N T D D T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001102146 481 54024 Y304 M Y G F V E P Y P D N T D D T
Dog Lupus familis XP_544379 453 51445 Y283 M Y G F A E P Y P D N T D D T
Cat Felis silvestris
Mouse Mus musculus Q9CWY3 473 52942 Y303 M Y G F A E P Y P N N T D D T
Rat Rattus norvegicus NP_001099637 474 53343 Y304 M Y G F A E P Y P N N T D D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507526 513 58286 Y343 M Y G F A E P Y P G N T D D T
Chicken Gallus gallus Q5ZK17 447 50631 Y276 M Y G F A E P Y P G N T N D T
Frog Xenopus laevis Q6INM2 455 52340 H283 M Y G F A E P H P Q N S N E T
Zebra Danio Brachydanio rerio Q803K4 460 52989 F282 M Y G F A E P F P N N I N E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181160 466 53174 Y298 M Y G F A E E Y P E N I Y D T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12504 494 57270 D282 R Y G Y V E W D G S K Y D F G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94.8 83.9 N.A. 77.1 77.6 N.A. 61.4 64.4 56.2 49 N.A. N.A. N.A. N.A. 40.8
Protein Similarity: 100 N.A. 95.8 86.8 N.A. 83.3 82.9 N.A. 71.1 76.1 71.2 67.8 N.A. N.A. N.A. N.A. 57.7
P-Site Identity: 100 N.A. 100 93.3 N.A. 86.6 86.6 N.A. 86.6 80 60 60 N.A. N.A. N.A. N.A. 66.6
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. 86.6 86.6 86.6 86.6 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 73 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 28 0 0 64 73 0 % D
% Glu: 0 0 0 0 0 100 10 0 0 10 0 0 0 19 0 % E
% Phe: 0 0 0 91 0 0 0 10 0 0 0 0 0 10 0 % F
% Gly: 0 0 100 0 0 0 0 0 10 19 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 91 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 28 91 0 28 0 0 % N
% Pro: 0 0 0 0 0 0 82 0 91 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 64 0 0 91 % T
% Val: 0 0 0 0 28 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 100 0 10 0 0 0 73 0 0 0 10 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _