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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZCCHC10 All Species: 15.15
Human Site: S135 Identified Species: 33.33
UniProt: Q8TBK6 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBK6 NP_060135.1 192 20967 S135 E E T S T S S S S E D S D T D
Chimpanzee Pan troglodytes XP_517929 192 20948 S135 E E T S T S S S S E D S D T D
Rhesus Macaque Macaca mulatta XP_001106397 192 20947 S135 E E T S T S S S S E D S D T D
Dog Lupus familis XP_531905 171 18564 S118 T S S S S E D S D T D E S S S
Cat Felis silvestris
Mouse Mus musculus Q9CX48 178 19129 S125 S D E S L S S S S S S S S S S
Rat Rattus norvegicus Q5EB97 173 18697 L120 D S D A D G S L S S S S S S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510156 171 18527 S118 T S S S S D D S D S E E S S S
Chicken Gallus gallus XP_414654 181 19546 D127 S S T S S S S D S D S D E S S
Frog Xenopus laevis NP_001087117 175 18940 K122 S S S E D S D K S T S S S S T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792574 117 12728 D64 E T S S G T I D S D S S S T L
Poplar Tree Populus trichocarpa XP_002314930 258 29305 G187 S G S S S V T G S E S S E E E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 99.4 85.9 N.A. 76 70.3 N.A. 73.4 70.8 64 N.A. N.A. N.A. N.A. N.A. 32.8
Protein Similarity: 100 100 100 88 N.A. 83.8 78.6 N.A. 81.2 80.2 75 N.A. N.A. N.A. N.A. N.A. 45.3
P-Site Identity: 100 100 100 20 N.A. 40 20 N.A. 13.3 33.3 20 N.A. N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 100 40 N.A. 53.3 40 N.A. 40 60 33.3 N.A. N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: 27.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 42.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 60 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 10 0 19 10 28 19 19 19 37 10 28 0 28 % D
% Glu: 37 28 10 10 0 10 0 0 0 37 10 19 19 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 10 10 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 37 46 46 82 37 55 55 55 82 28 55 73 55 55 46 % S
% Thr: 19 10 37 0 28 10 10 0 0 19 0 0 0 37 10 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _