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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC10
All Species:
28.79
Human Site:
S148
Identified Species:
63.33
UniProt:
Q8TBK6
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBK6
NP_060135.1
192
20967
S148
T
D
E
S
S
S
S
S
S
S
S
A
S
S
T
Chimpanzee
Pan troglodytes
XP_517929
192
20948
S148
T
D
E
S
S
S
S
S
S
S
S
A
S
S
T
Rhesus Macaque
Macaca mulatta
XP_001106397
192
20947
S148
T
D
E
S
S
S
S
S
S
S
S
A
S
S
T
Dog
Lupus familis
XP_531905
171
18564
S131
S
S
S
S
S
S
S
S
S
S
T
S
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX48
178
19129
S138
S
S
A
C
S
S
S
S
S
S
S
S
S
S
S
Rat
Rattus norvegicus
Q5EB97
173
18697
S133
S
S
A
Y
S
S
S
S
S
S
S
S
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510156
171
18527
R131
S
S
S
S
S
T
S
R
S
S
T
S
S
S
S
Chicken
Gallus gallus
XP_414654
181
19546
S140
S
S
S
T
S
S
S
S
P
S
S
S
S
T
S
Frog
Xenopus laevis
NP_001087117
175
18940
S135
S
T
S
L
S
S
Q
S
S
S
S
S
E
C
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792574
117
12728
E77
T
L
S
S
S
D
D
E
S
S
D
E
D
S
N
Poplar Tree
Populus trichocarpa
XP_002314930
258
29305
S200
E
E
S
S
S
G
Y
S
S
S
S
S
E
E
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
99.4
85.9
N.A.
76
70.3
N.A.
73.4
70.8
64
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
100
100
100
88
N.A.
83.8
78.6
N.A.
81.2
80.2
75
N.A.
N.A.
N.A.
N.A.
N.A.
45.3
P-Site Identity:
100
100
100
60
N.A.
60
60
N.A.
46.6
46.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
80
80
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
27.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
42.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
0
0
0
0
0
0
28
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
28
0
0
0
10
10
0
0
0
10
0
10
0
10
% D
% Glu:
10
10
28
0
0
0
0
10
0
0
0
10
19
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
55
46
55
64
100
73
73
82
91
100
73
64
73
73
46
% S
% Thr:
37
10
0
10
0
10
0
0
0
0
19
0
0
10
28
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _