KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC10
All Species:
12.12
Human Site:
S181
Identified Species:
26.67
UniProt:
Q8TBK6
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBK6
NP_060135.1
192
20967
S181
S
T
S
T
D
S
S
S
D
D
E
P
P
K
K
Chimpanzee
Pan troglodytes
XP_517929
192
20948
S181
S
T
S
T
D
S
S
S
D
D
E
P
P
K
K
Rhesus Macaque
Macaca mulatta
XP_001106397
192
20947
S181
S
T
S
T
D
S
S
S
D
D
E
P
P
K
K
Dog
Lupus familis
XP_531905
171
18564
P164
E
S
S
S
E
D
E
P
P
K
K
K
K
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CX48
178
19129
Q171
S
S
S
D
D
E
P
Q
K
K
K
K
K
K
K
Rat
Rattus norvegicus
Q5EB97
173
18697
P166
E
S
S
S
D
D
E
P
P
K
K
R
K
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510156
171
18527
P164
D
S
S
S
D
D
E
P
P
K
K
K
K
K
K
Chicken
Gallus gallus
XP_414654
181
19546
E173
T
D
S
S
S
D
D
E
P
P
K
K
K
K
K
Frog
Xenopus laevis
NP_001087117
175
18940
P168
D
S
S
S
E
D
E
P
L
R
K
K
R
K
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792574
117
12728
V110
S
D
S
S
E
D
S
V
P
R
K
K
R
K
R
Poplar Tree
Populus trichocarpa
XP_002314930
258
29305
S233
S
S
S
S
D
E
S
S
D
S
D
S
G
S
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
99.4
85.9
N.A.
76
70.3
N.A.
73.4
70.8
64
N.A.
N.A.
N.A.
N.A.
N.A.
32.8
Protein Similarity:
100
100
100
88
N.A.
83.8
78.6
N.A.
81.2
80.2
75
N.A.
N.A.
N.A.
N.A.
N.A.
45.3
P-Site Identity:
100
100
100
20
N.A.
33.3
26.6
N.A.
26.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
46.6
N.A.
46.6
46.6
N.A.
46.6
40
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
27.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
42.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
19
0
10
64
55
10
0
37
28
10
0
0
0
0
% D
% Glu:
19
0
0
0
28
19
37
10
0
0
28
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
37
64
55
46
91
82
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
37
46
10
0
28
28
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
19
0
10
19
0
10
% R
% Ser:
55
55
100
64
10
28
46
37
0
10
0
10
0
10
0
% S
% Thr:
10
28
0
28
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _