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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBC1D16 All Species: 24.55
Human Site: S212 Identified Species: 38.57
UniProt: Q8TBP0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBP0 NP_061893.2 767 86372 S212 E A G E E D G S L E L S A E G
Chimpanzee Pan troglodytes XP_001159856 767 86325 S212 E A G E E D G S L E L S A E G
Rhesus Macaque Macaca mulatta XP_001109890 767 86411 S212 E A G E E D G S L E L S A E G
Dog Lupus familis XP_540469 762 85478 S208 E A G E E E G S L E L S A D G
Cat Felis silvestris
Mouse Mus musculus Q9CXF4 671 76509 G168 P A L H F H Q G D S K L L I E
Rat Rattus norvegicus XP_221188 766 86483 S211 E A V E E E G S L E L S A D G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510430 604 65814 P101 E A L R Y V T P E S S P V R K
Chicken Gallus gallus XP_001231439 765 86401 S218 E P G E D E G S L E L F A D D
Frog Xenopus laevis NP_001079950 727 83313 S202 S E A L G E S S S S A F L E N
Zebra Danio Brachydanio rerio XP_001921969 203 23650
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609403 702 80725 T197 S Q S F N C I T I R P D S N N
Honey Bee Apis mellifera XP_396806 769 88817 K239 Y D E N Q Y C K D Q K I S E T
Nematode Worm Caenorhab. elegans NP_508988 744 85313 E214 R T E N A K D E S D K M S Q S
Sea Urchin Strong. purpuratus XP_787939 808 91830 S273 N N I L E R L S N D V L P R Q
Poplar Tree Populus trichocarpa XP_002308065 487 56118
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.9 88.7 N.A. 23.3 88.6 N.A. 58.7 78.6 71.7 20.9 N.A. 42.2 41.3 35.4 44.1
Protein Similarity: 100 99.8 98.4 92.5 N.A. 40.6 91.9 N.A. 64.5 86.6 81.2 23.3 N.A. 58.7 56.9 54.1 60.8
P-Site Identity: 100 100 100 86.6 N.A. 6.6 80 N.A. 13.3 60 13.3 0 N.A. 0 6.6 0 13.3
P-Site Similarity: 100 100 100 100 N.A. 6.6 93.3 N.A. 13.3 80 20 0 N.A. 20 26.6 20 26.6
Percent
Protein Identity: 26.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 41.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 0 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 47 7 0 7 0 0 0 0 0 7 0 40 0 0 % A
% Cys: 0 0 0 0 0 7 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 7 20 7 0 14 14 0 7 0 20 7 % D
% Glu: 47 7 14 40 40 27 0 7 7 40 0 0 0 34 7 % E
% Phe: 0 0 0 7 7 0 0 0 0 0 0 14 0 0 0 % F
% Gly: 0 0 34 0 7 0 40 7 0 0 0 0 0 0 34 % G
% His: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 7 0 7 0 0 7 0 7 0 % I
% Lys: 0 0 0 0 0 7 0 7 0 0 20 0 0 0 7 % K
% Leu: 0 0 14 14 0 0 7 0 40 0 40 14 14 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 7 7 0 14 7 0 0 0 7 0 0 0 0 7 14 % N
% Pro: 7 7 0 0 0 0 0 7 0 0 7 7 7 0 0 % P
% Gln: 0 7 0 0 7 0 7 0 0 7 0 0 0 7 7 % Q
% Arg: 7 0 0 7 0 7 0 0 0 7 0 0 0 14 0 % R
% Ser: 14 0 7 0 0 0 7 54 14 20 7 34 20 0 7 % S
% Thr: 0 7 0 0 0 0 7 7 0 0 0 0 0 0 7 % T
% Val: 0 0 7 0 0 7 0 0 0 0 7 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 7 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _