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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D16
All Species:
25.45
Human Site:
S225
Identified Species:
40
UniProt:
Q8TBP0
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP0
NP_061893.2
767
86372
S225
E
G
V
S
R
D
S
S
F
D
S
D
S
D
T
Chimpanzee
Pan troglodytes
XP_001159856
767
86325
S225
E
G
V
S
R
D
S
S
F
D
S
D
S
D
T
Rhesus Macaque
Macaca mulatta
XP_001109890
767
86411
S225
E
G
V
S
R
D
S
S
F
D
S
D
S
D
A
Dog
Lupus familis
XP_540469
762
85478
S221
D
G
V
S
R
D
S
S
F
D
S
D
S
D
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
V181
I
E
S
L
E
K
Y
V
V
L
C
E
S
P
Q
Rat
Rattus norvegicus
XP_221188
766
86483
S224
D
G
V
S
R
D
S
S
F
D
S
D
S
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510430
604
65814
G114
R
K
A
P
R
K
R
G
G
R
A
H
A
A
P
Chicken
Gallus gallus
XP_001231439
765
86401
T231
D
D
V
S
R
D
S
T
F
D
S
D
S
D
A
Frog
Xenopus laevis
NP_001079950
727
83313
S215
E
N
E
N
R
D
E
S
N
S
H
M
S
S
Y
Zebra Danio
Brachydanio rerio
XP_001921969
203
23650
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609403
702
80725
N210
N
N
C
S
D
C
T
N
G
S
G
V
G
D
G
Honey Bee
Apis mellifera
XP_396806
769
88817
I252
E
T
H
E
S
D
G
I
S
I
D
E
E
L
K
Nematode Worm
Caenorhab. elegans
NP_508988
744
85313
C227
Q
S
S
L
S
T
S
C
A
D
E
M
S
D
K
Sea Urchin
Strong. purpuratus
XP_787939
808
91830
S286
R
Q
M
S
R
R
S
S
S
T
T
P
T
T
S
Poplar Tree
Populus trichocarpa
XP_002308065
487
56118
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
88.7
N.A.
23.3
88.6
N.A.
58.7
78.6
71.7
20.9
N.A.
42.2
41.3
35.4
44.1
Protein Similarity:
100
99.8
98.4
92.5
N.A.
40.6
91.9
N.A.
64.5
86.6
81.2
23.3
N.A.
58.7
56.9
54.1
60.8
P-Site Identity:
100
100
93.3
86.6
N.A.
6.6
86.6
N.A.
6.6
73.3
33.3
0
N.A.
13.3
13.3
26.6
26.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
13.3
93.3
N.A.
20
86.6
40
0
N.A.
26.6
20
33.3
53.3
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
7
0
7
0
7
7
27
% A
% Cys:
0
0
7
0
0
7
0
7
0
0
7
0
0
0
0
% C
% Asp:
20
7
0
0
7
54
0
0
0
47
7
40
0
54
0
% D
% Glu:
34
7
7
7
7
0
7
0
0
0
7
14
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% F
% Gly:
0
34
0
0
0
0
7
7
14
0
7
0
7
0
7
% G
% His:
0
0
7
0
0
0
0
0
0
0
7
7
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
14
0
0
0
0
0
0
0
0
14
% K
% Leu:
0
0
0
14
0
0
0
0
0
7
0
0
0
7
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
14
0
0
0
% M
% Asn:
7
14
0
7
0
0
0
7
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
0
0
7
0
7
7
% P
% Gln:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
14
0
0
0
60
7
7
0
0
7
0
0
0
0
0
% R
% Ser:
0
7
14
54
14
0
54
47
14
14
40
0
60
7
7
% S
% Thr:
0
7
0
0
0
7
7
7
0
7
7
0
7
7
14
% T
% Val:
0
0
40
0
0
0
0
7
7
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _