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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D16
All Species:
19.39
Human Site:
S252
Identified Species:
30.48
UniProt:
Q8TBP0
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP0
NP_061893.2
767
86372
S252
A
L
A
E
S
R
G
S
V
F
L
E
S
D
S
Chimpanzee
Pan troglodytes
XP_001159856
767
86325
S252
A
L
A
E
S
R
G
S
V
F
L
E
S
D
S
Rhesus Macaque
Macaca mulatta
XP_001109890
767
86411
S252
A
L
A
E
S
R
G
S
V
F
L
E
S
D
S
Dog
Lupus familis
XP_540469
762
85478
S248
A
L
G
D
S
G
S
S
V
F
L
D
S
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
N208
S
L
S
Q
S
F
E
N
L
L
D
E
P
A
Y
Rat
Rattus norvegicus
XP_221188
766
86483
S251
A
L
A
E
G
N
S
S
A
F
L
E
S
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510430
604
65814
G141
A
S
P
S
S
E
D
G
D
R
R
P
R
S
A
Chicken
Gallus gallus
XP_001231439
765
86401
S258
A
L
V
K
S
S
S
S
V
F
L
D
N
E
S
Frog
Xenopus laevis
NP_001079950
727
83313
A242
N
N
G
Q
G
V
P
A
R
W
E
E
Q
Q
K
Zebra Danio
Brachydanio rerio
XP_001921969
203
23650
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609403
702
80725
L237
L
L
A
F
K
H
N
L
E
F
P
D
S
G
N
Honey Bee
Apis mellifera
XP_396806
769
88817
C279
S
M
S
L
T
S
T
C
S
L
S
V
G
V
S
Nematode Worm
Caenorhab. elegans
NP_508988
744
85313
G254
E
K
P
D
P
G
V
G
L
E
K
I
L
E
S
Sea Urchin
Strong. purpuratus
XP_787939
808
91830
F313
P
E
E
S
F
D
P
F
V
P
L
Y
S
L
H
Poplar Tree
Populus trichocarpa
XP_002308065
487
56118
P24
P
V
Y
I
A
S
G
P
S
A
S
V
S
D
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
88.7
N.A.
23.3
88.6
N.A.
58.7
78.6
71.7
20.9
N.A.
42.2
41.3
35.4
44.1
Protein Similarity:
100
99.8
98.4
92.5
N.A.
40.6
91.9
N.A.
64.5
86.6
81.2
23.3
N.A.
58.7
56.9
54.1
60.8
P-Site Identity:
100
100
100
60
N.A.
20
60
N.A.
13.3
53.3
6.6
0
N.A.
26.6
6.6
6.6
20
P-Site Similarity:
100
100
100
80
N.A.
53.3
66.6
N.A.
20
80
26.6
0
N.A.
40
33.3
26.6
20
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
34
0
7
0
0
7
7
7
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
14
0
7
7
0
7
0
7
20
0
27
0
% D
% Glu:
7
7
7
27
0
7
7
0
7
7
7
40
0
27
0
% E
% Phe:
0
0
0
7
7
7
0
7
0
47
0
0
0
0
0
% F
% Gly:
0
0
14
0
14
14
27
14
0
0
0
0
7
7
14
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
0
7
0
7
7
0
0
0
0
0
7
0
0
0
7
% K
% Leu:
7
54
0
7
0
0
0
7
14
14
47
0
7
7
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
7
7
7
0
0
0
0
7
0
7
% N
% Pro:
14
0
14
0
7
0
14
7
0
7
7
7
7
0
0
% P
% Gln:
0
0
0
14
0
0
0
0
0
0
0
0
7
7
0
% Q
% Arg:
0
0
0
0
0
20
0
0
7
7
7
0
7
0
0
% R
% Ser:
14
7
14
14
47
20
20
40
14
0
14
0
54
7
47
% S
% Thr:
0
0
0
0
7
0
7
0
0
0
0
0
0
0
0
% T
% Val:
0
7
7
0
0
7
7
0
40
0
0
14
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _