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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D16
All Species:
19.09
Human Site:
S259
Identified Species:
30
UniProt:
Q8TBP0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP0
NP_061893.2
767
86372
S259
S
V
F
L
E
S
D
S
S
P
P
S
S
S
D
Chimpanzee
Pan troglodytes
XP_001159856
767
86325
S259
S
V
F
L
E
S
D
S
S
P
P
S
S
S
D
Rhesus Macaque
Macaca mulatta
XP_001109890
767
86411
S259
S
V
F
L
E
S
D
S
S
P
P
S
S
S
D
Dog
Lupus familis
XP_540469
762
85478
S255
S
V
F
L
D
S
E
S
G
S
P
S
G
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
Y215
N
L
L
D
E
P
A
Y
G
L
I
Q
K
I
K
Rat
Rattus norvegicus
XP_221188
766
86483
G258
S
A
F
L
E
S
E
G
S
S
P
S
S
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510430
604
65814
A148
G
D
R
R
P
R
S
A
G
S
V
G
P
P
G
Chicken
Gallus gallus
XP_001231439
765
86401
S265
S
V
F
L
D
N
E
S
S
P
N
G
S
T
Q
Frog
Xenopus laevis
NP_001079950
727
83313
K249
A
R
W
E
E
Q
Q
K
L
L
A
L
E
H
T
Zebra Danio
Brachydanio rerio
XP_001921969
203
23650
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609403
702
80725
N244
L
E
F
P
D
S
G
N
S
T
P
A
D
R
Q
Honey Bee
Apis mellifera
XP_396806
769
88817
S286
C
S
L
S
V
G
V
S
S
E
A
E
E
I
P
Nematode Worm
Caenorhab. elegans
NP_508988
744
85313
S261
G
L
E
K
I
L
E
S
T
Q
M
F
D
K
T
Sea Urchin
Strong. purpuratus
XP_787939
808
91830
H320
F
V
P
L
Y
S
L
H
S
S
S
T
C
S
P
Poplar Tree
Populus trichocarpa
XP_002308065
487
56118
G31
P
S
A
S
V
S
D
G
G
E
S
S
S
C
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
88.7
N.A.
23.3
88.6
N.A.
58.7
78.6
71.7
20.9
N.A.
42.2
41.3
35.4
44.1
Protein Similarity:
100
99.8
98.4
92.5
N.A.
40.6
91.9
N.A.
64.5
86.6
81.2
23.3
N.A.
58.7
56.9
54.1
60.8
P-Site Identity:
100
100
100
60
N.A.
6.6
73.3
N.A.
0
53.3
6.6
0
N.A.
26.6
13.3
6.6
33.3
P-Site Similarity:
100
100
100
80
N.A.
20
80
N.A.
6.6
80
20
0
N.A.
46.6
13.3
26.6
40
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
0
0
7
7
0
0
14
7
0
7
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% C
% Asp:
0
7
0
7
20
0
27
0
0
0
0
0
14
0
34
% D
% Glu:
0
7
7
7
40
0
27
0
0
14
0
7
14
0
7
% E
% Phe:
7
0
47
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
14
0
0
0
0
7
7
14
27
0
0
14
7
0
7
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
0
7
0
0
14
0
% I
% Lys:
0
0
0
7
0
0
0
7
0
0
0
0
7
7
7
% K
% Leu:
7
14
14
47
0
7
7
0
7
14
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
0
0
0
0
7
0
7
0
0
7
0
0
0
0
% N
% Pro:
7
0
7
7
7
7
0
0
0
27
40
0
7
7
14
% P
% Gln:
0
0
0
0
0
7
7
0
0
7
0
7
0
0
14
% Q
% Arg:
0
7
7
7
0
7
0
0
0
0
0
0
0
7
0
% R
% Ser:
40
14
0
14
0
54
7
47
54
27
14
40
40
34
0
% S
% Thr:
0
0
0
0
0
0
0
0
7
7
0
7
0
7
14
% T
% Val:
0
40
0
0
14
0
7
0
0
0
7
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _