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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBC1D16 All Species: 19.09
Human Site: S259 Identified Species: 30
UniProt: Q8TBP0 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBP0 NP_061893.2 767 86372 S259 S V F L E S D S S P P S S S D
Chimpanzee Pan troglodytes XP_001159856 767 86325 S259 S V F L E S D S S P P S S S D
Rhesus Macaque Macaca mulatta XP_001109890 767 86411 S259 S V F L E S D S S P P S S S D
Dog Lupus familis XP_540469 762 85478 S255 S V F L D S E S G S P S G A D
Cat Felis silvestris
Mouse Mus musculus Q9CXF4 671 76509 Y215 N L L D E P A Y G L I Q K I K
Rat Rattus norvegicus XP_221188 766 86483 G258 S A F L E S E G S S P S S S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510430 604 65814 A148 G D R R P R S A G S V G P P G
Chicken Gallus gallus XP_001231439 765 86401 S265 S V F L D N E S S P N G S T Q
Frog Xenopus laevis NP_001079950 727 83313 K249 A R W E E Q Q K L L A L E H T
Zebra Danio Brachydanio rerio XP_001921969 203 23650
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609403 702 80725 N244 L E F P D S G N S T P A D R Q
Honey Bee Apis mellifera XP_396806 769 88817 S286 C S L S V G V S S E A E E I P
Nematode Worm Caenorhab. elegans NP_508988 744 85313 S261 G L E K I L E S T Q M F D K T
Sea Urchin Strong. purpuratus XP_787939 808 91830 H320 F V P L Y S L H S S S T C S P
Poplar Tree Populus trichocarpa XP_002308065 487 56118 G31 P S A S V S D G G E S S S C E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.9 88.7 N.A. 23.3 88.6 N.A. 58.7 78.6 71.7 20.9 N.A. 42.2 41.3 35.4 44.1
Protein Similarity: 100 99.8 98.4 92.5 N.A. 40.6 91.9 N.A. 64.5 86.6 81.2 23.3 N.A. 58.7 56.9 54.1 60.8
P-Site Identity: 100 100 100 60 N.A. 6.6 73.3 N.A. 0 53.3 6.6 0 N.A. 26.6 13.3 6.6 33.3
P-Site Similarity: 100 100 100 80 N.A. 20 80 N.A. 6.6 80 20 0 N.A. 46.6 13.3 26.6 40
Percent
Protein Identity: 26.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 41.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 0 0 7 7 0 0 14 7 0 7 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % C
% Asp: 0 7 0 7 20 0 27 0 0 0 0 0 14 0 34 % D
% Glu: 0 7 7 7 40 0 27 0 0 14 0 7 14 0 7 % E
% Phe: 7 0 47 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 14 0 0 0 0 7 7 14 27 0 0 14 7 0 7 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 7 0 % H
% Ile: 0 0 0 0 7 0 0 0 0 0 7 0 0 14 0 % I
% Lys: 0 0 0 7 0 0 0 7 0 0 0 0 7 7 7 % K
% Leu: 7 14 14 47 0 7 7 0 7 14 0 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 7 0 0 0 0 7 0 7 0 0 7 0 0 0 0 % N
% Pro: 7 0 7 7 7 7 0 0 0 27 40 0 7 7 14 % P
% Gln: 0 0 0 0 0 7 7 0 0 7 0 7 0 0 14 % Q
% Arg: 0 7 7 7 0 7 0 0 0 0 0 0 0 7 0 % R
% Ser: 40 14 0 14 0 54 7 47 54 27 14 40 40 34 0 % S
% Thr: 0 0 0 0 0 0 0 0 7 7 0 7 0 7 14 % T
% Val: 0 40 0 0 14 0 7 0 0 0 7 0 0 0 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _