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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D16
All Species:
13.94
Human Site:
S274
Identified Species:
21.9
UniProt:
Q8TBP0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP0
NP_061893.2
767
86372
S274
A
G
L
R
F
P
D
S
N
G
L
L
Q
T
P
Chimpanzee
Pan troglodytes
XP_001159856
767
86325
S274
A
G
L
R
F
P
D
S
N
G
L
L
Q
T
P
Rhesus Macaque
Macaca mulatta
XP_001109890
767
86411
S274
T
G
L
R
F
P
D
S
N
G
L
L
Q
T
P
Dog
Lupus familis
XP_540469
762
85478
G270
A
H
L
R
F
P
D
G
T
G
L
L
Q
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
M230
K
D
P
Y
T
A
T
M
V
G
F
S
K
V
T
Rat
Rattus norvegicus
XP_221188
766
86483
S273
A
N
L
R
F
P
D
S
N
G
L
L
Q
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510430
604
65814
D163
T
P
R
S
A
R
G
D
S
G
S
S
W
T
V
Chicken
Gallus gallus
XP_001231439
765
86401
A280
S
P
E
S
S
G
Q
A
Q
G
E
E
Q
Q
K
Frog
Xenopus laevis
NP_001079950
727
83313
L264
C
G
V
F
R
V
D
L
G
Q
M
R
S
L
R
Zebra Danio
Brachydanio rerio
XP_001921969
203
23650
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609403
702
80725
H259
K
S
A
M
K
C
R
H
F
S
V
D
L
S
Q
Honey Bee
Apis mellifera
XP_396806
769
88817
L301
S
W
M
R
S
P
E
L
L
A
L
Q
H
N
L
Nematode Worm
Caenorhab. elegans
NP_508988
744
85313
H276
P
E
Q
F
A
L
E
H
D
L
M
L
T
D
T
Sea Urchin
Strong. purpuratus
XP_787939
808
91830
A335
E
F
H
P
S
P
I
A
T
H
N
M
T
F
P
Poplar Tree
Populus trichocarpa
XP_002308065
487
56118
S46
L
Q
E
R
I
G
D
S
I
R
D
E
I
P
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
88.7
N.A.
23.3
88.6
N.A.
58.7
78.6
71.7
20.9
N.A.
42.2
41.3
35.4
44.1
Protein Similarity:
100
99.8
98.4
92.5
N.A.
40.6
91.9
N.A.
64.5
86.6
81.2
23.3
N.A.
58.7
56.9
54.1
60.8
P-Site Identity:
100
100
93.3
80
N.A.
6.6
93.3
N.A.
13.3
13.3
13.3
0
N.A.
0
20
6.6
13.3
P-Site Similarity:
100
100
93.3
80
N.A.
13.3
93.3
N.A.
20
26.6
26.6
0
N.A.
13.3
40
26.6
26.6
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
0
7
0
14
7
0
14
0
7
0
0
0
0
0
% A
% Cys:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
47
7
7
0
7
7
0
7
0
% D
% Glu:
7
7
14
0
0
0
14
0
0
0
7
14
0
0
0
% E
% Phe:
0
7
0
14
34
0
0
0
7
0
7
0
0
7
0
% F
% Gly:
0
27
0
0
0
14
7
7
7
54
0
0
0
0
0
% G
% His:
0
7
7
0
0
0
0
14
0
7
0
0
7
0
0
% H
% Ile:
0
0
0
0
7
0
7
0
7
0
0
0
7
0
0
% I
% Lys:
14
0
0
0
7
0
0
0
0
0
0
0
7
0
7
% K
% Leu:
7
0
34
0
0
7
0
14
7
7
40
40
7
7
7
% L
% Met:
0
0
7
7
0
0
0
7
0
0
14
7
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
27
0
7
0
0
7
0
% N
% Pro:
7
14
7
7
0
47
0
0
0
0
0
0
0
7
40
% P
% Gln:
0
7
7
0
0
0
7
0
7
7
0
7
40
7
7
% Q
% Arg:
0
0
7
47
7
7
7
0
0
7
0
7
0
0
14
% R
% Ser:
14
7
0
14
20
0
0
34
7
7
7
14
7
7
0
% S
% Thr:
14
0
0
0
7
0
7
0
14
0
0
0
14
40
14
% T
% Val:
0
0
7
0
0
7
0
0
7
0
7
0
0
7
7
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _