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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D16
All Species:
20
Human Site:
S383
Identified Species:
31.43
UniProt:
Q8TBP0
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP0
NP_061893.2
767
86372
S383
I
R
R
P
K
L
P
S
S
E
T
H
P
E
E
Chimpanzee
Pan troglodytes
XP_001159856
767
86325
S383
I
R
R
P
K
L
P
S
S
E
T
H
P
E
E
Rhesus Macaque
Macaca mulatta
XP_001109890
767
86411
S383
I
R
R
P
K
L
P
S
S
E
T
H
P
E
E
Dog
Lupus familis
XP_540469
762
85478
S379
R
R
P
K
L
P
S
S
E
T
H
P
E
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
F326
E
S
M
K
Q
K
I
F
R
G
G
L
S
H
S
Rat
Rattus norvegicus
XP_221188
766
86483
S382
I
R
R
P
K
L
P
S
S
E
I
H
P
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510430
604
65814
N259
P
N
S
R
F
S
E
N
G
G
Q
P
Q
N
G
Chicken
Gallus gallus
XP_001231439
765
86401
S382
I
R
R
P
K
L
P
S
S
E
T
H
P
E
E
Frog
Xenopus laevis
NP_001079950
727
83313
T360
M
Y
R
R
L
D
V
T
S
W
L
E
H
L
N
Zebra Danio
Brachydanio rerio
XP_001921969
203
23650
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609403
702
80725
K356
H
P
D
E
G
D
V
K
K
I
T
T
N
F
F
Honey Bee
Apis mellifera
XP_396806
769
88817
D414
C
R
P
E
V
S
R
D
E
L
H
P
E
E
G
Nematode Worm
Caenorhab. elegans
NP_508988
744
85313
V389
C
Q
P
A
V
T
K
V
E
K
D
P
E
E
G
Sea Urchin
Strong. purpuratus
XP_787939
808
91830
P453
I
I
Q
S
S
M
K
P
E
D
C
H
P
E
E
Poplar Tree
Populus trichocarpa
XP_002308065
487
56118
F142
V
P
S
D
P
L
E
F
D
K
M
T
L
V
W
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
88.7
N.A.
23.3
88.6
N.A.
58.7
78.6
71.7
20.9
N.A.
42.2
41.3
35.4
44.1
Protein Similarity:
100
99.8
98.4
92.5
N.A.
40.6
91.9
N.A.
64.5
86.6
81.2
23.3
N.A.
58.7
56.9
54.1
60.8
P-Site Identity:
100
100
100
20
N.A.
0
93.3
N.A.
0
100
13.3
0
N.A.
6.6
13.3
6.6
33.3
P-Site Similarity:
100
100
100
20
N.A.
6.6
93.3
N.A.
6.6
100
26.6
0
N.A.
6.6
13.3
20
53.3
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
14
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
7
7
0
14
0
7
7
7
7
0
0
0
0
% D
% Glu:
7
0
0
14
0
0
14
0
27
34
0
7
20
60
40
% E
% Phe:
0
0
0
0
7
0
0
14
0
0
0
0
0
7
7
% F
% Gly:
0
0
0
0
7
0
0
0
7
14
7
0
0
0
20
% G
% His:
7
0
0
0
0
0
0
0
0
0
14
40
7
7
0
% H
% Ile:
40
7
0
0
0
0
7
0
0
7
7
0
0
0
0
% I
% Lys:
0
0
0
14
34
7
14
7
7
14
0
0
0
0
0
% K
% Leu:
0
0
0
0
14
40
0
0
0
7
7
7
7
7
0
% L
% Met:
7
0
7
0
0
7
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
7
0
0
0
0
7
7
7
% N
% Pro:
7
14
20
34
7
7
34
7
0
0
0
27
40
0
0
% P
% Gln:
0
7
7
0
7
0
0
0
0
0
7
0
7
0
0
% Q
% Arg:
7
47
40
14
0
0
7
0
7
0
0
0
0
0
0
% R
% Ser:
0
7
14
7
7
14
7
40
40
0
0
0
7
0
14
% S
% Thr:
0
0
0
0
0
7
0
7
0
7
34
14
0
0
0
% T
% Val:
7
0
0
0
14
0
14
7
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% W
% Tyr:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _