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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBC1D16 All Species: 18.79
Human Site: S384 Identified Species: 29.52
UniProt: Q8TBP0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBP0 NP_061893.2 767 86372 S384 R R P K L P S S E T H P E E S
Chimpanzee Pan troglodytes XP_001159856 767 86325 S384 R R P K L P S S E T H P E E S
Rhesus Macaque Macaca mulatta XP_001109890 767 86411 S384 R R P K L P S S E T H P E E S
Dog Lupus familis XP_540469 762 85478 E380 R P K L P S S E T H P E E S M
Cat Felis silvestris
Mouse Mus musculus Q9CXF4 671 76509 R327 S M K Q K I F R G G L S H S L
Rat Rattus norvegicus XP_221188 766 86483 S383 R R P K L P S S E I H P E E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510430 604 65814 G260 N S R F S E N G G Q P Q N G K
Chicken Gallus gallus XP_001231439 765 86401 S383 R R P K L P S S E T H P E E N
Frog Xenopus laevis NP_001079950 727 83313 S361 Y R R L D V T S W L E H L N E
Zebra Danio Brachydanio rerio XP_001921969 203 23650
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609403 702 80725 K357 P D E G D V K K I T T N F F Y
Honey Bee Apis mellifera XP_396806 769 88817 E415 R P E V S R D E L H P E E G Q
Nematode Worm Caenorhab. elegans NP_508988 744 85313 E390 Q P A V T K V E K D P E E G L
Sea Urchin Strong. purpuratus XP_787939 808 91830 E454 I Q S S M K P E D C H P E E G
Poplar Tree Populus trichocarpa XP_002308065 487 56118 D143 P S D P L E F D K M T L V W G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.9 88.7 N.A. 23.3 88.6 N.A. 58.7 78.6 71.7 20.9 N.A. 42.2 41.3 35.4 44.1
Protein Similarity: 100 99.8 98.4 92.5 N.A. 40.6 91.9 N.A. 64.5 86.6 81.2 23.3 N.A. 58.7 56.9 54.1 60.8
P-Site Identity: 100 100 100 20 N.A. 0 93.3 N.A. 0 93.3 13.3 0 N.A. 6.6 13.3 6.6 26.6
P-Site Similarity: 100 100 100 20 N.A. 6.6 93.3 N.A. 6.6 100 20 0 N.A. 6.6 13.3 20 46.6
Percent
Protein Identity: 26.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 41.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % C
% Asp: 0 7 7 0 14 0 7 7 7 7 0 0 0 0 0 % D
% Glu: 0 0 14 0 0 14 0 27 34 0 7 20 60 40 7 % E
% Phe: 0 0 0 7 0 0 14 0 0 0 0 0 7 7 0 % F
% Gly: 0 0 0 7 0 0 0 7 14 7 0 0 0 20 14 % G
% His: 0 0 0 0 0 0 0 0 0 14 40 7 7 0 0 % H
% Ile: 7 0 0 0 0 7 0 0 7 7 0 0 0 0 0 % I
% Lys: 0 0 14 34 7 14 7 7 14 0 0 0 0 0 7 % K
% Leu: 0 0 0 14 40 0 0 0 7 7 7 7 7 0 14 % L
% Met: 0 7 0 0 7 0 0 0 0 7 0 0 0 0 7 % M
% Asn: 7 0 0 0 0 0 7 0 0 0 0 7 7 7 7 % N
% Pro: 14 20 34 7 7 34 7 0 0 0 27 40 0 0 0 % P
% Gln: 7 7 0 7 0 0 0 0 0 7 0 7 0 0 7 % Q
% Arg: 47 40 14 0 0 7 0 7 0 0 0 0 0 0 0 % R
% Ser: 7 14 7 7 14 7 40 40 0 0 0 7 0 14 27 % S
% Thr: 0 0 0 0 7 0 7 0 7 34 14 0 0 0 0 % T
% Val: 0 0 0 14 0 14 7 0 0 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _