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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D16
All Species:
24.85
Human Site:
S512
Identified Species:
39.05
UniProt:
Q8TBP0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP0
NP_061893.2
767
86372
S512
E
D
N
P
N
V
E
S
M
R
R
I
L
L
N
Chimpanzee
Pan troglodytes
XP_001159856
767
86325
S512
E
D
N
P
N
V
E
S
M
R
R
I
L
L
N
Rhesus Macaque
Macaca mulatta
XP_001109890
767
86411
S512
E
D
N
P
N
V
E
S
M
R
R
I
L
L
N
Dog
Lupus familis
XP_540469
762
85478
S507
E
D
N
P
N
V
E
S
M
R
R
I
L
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
N452
P
L
L
Y
V
M
E
N
E
V
D
A
F
W
C
Rat
Rattus norvegicus
XP_221188
766
86483
S511
E
D
N
P
N
V
E
S
M
R
R
I
L
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510430
604
65814
S385
L
A
E
V
L
D
E
S
D
A
F
W
C
F
V
Chicken
Gallus gallus
XP_001231439
765
86401
T511
E
N
N
P
N
V
E
T
M
R
R
I
L
L
N
Frog
Xenopus laevis
NP_001079950
727
83313
Y490
V
Y
S
P
G
V
G
Y
S
Q
G
M
S
D
L
Zebra Danio
Brachydanio rerio
XP_001921969
203
23650
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609403
702
80725
L482
E
V
M
K
N
I
L
L
N
F
A
V
Y
N
T
Honey Bee
Apis mellifera
XP_396806
769
88817
I542
E
D
N
P
N
I
E
I
M
K
N
I
L
L
N
Nematode Worm
Caenorhab. elegans
NP_508988
744
85313
I516
D
N
N
P
N
S
E
I
M
K
N
I
L
L
N
Sea Urchin
Strong. purpuratus
XP_787939
808
91830
I582
E
N
N
P
N
V
D
I
M
R
N
I
L
V
N
Poplar Tree
Populus trichocarpa
XP_002308065
487
56118
D268
A
L
S
F
Y
D
G
D
D
N
P
N
V
N
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
88.7
N.A.
23.3
88.6
N.A.
58.7
78.6
71.7
20.9
N.A.
42.2
41.3
35.4
44.1
Protein Similarity:
100
99.8
98.4
92.5
N.A.
40.6
91.9
N.A.
64.5
86.6
81.2
23.3
N.A.
58.7
56.9
54.1
60.8
P-Site Identity:
100
100
100
100
N.A.
6.6
100
N.A.
13.3
86.6
13.3
0
N.A.
13.3
73.3
60
66.6
P-Site Similarity:
100
100
100
100
N.A.
20
100
N.A.
13.3
100
33.3
0
N.A.
26.6
86.6
80
86.6
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
0
0
7
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% C
% Asp:
7
40
0
0
0
14
7
7
14
0
7
0
0
7
0
% D
% Glu:
60
0
7
0
0
0
67
0
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
7
7
0
7
7
0
% F
% Gly:
0
0
0
0
7
0
14
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
14
0
20
0
0
0
60
0
0
7
% I
% Lys:
0
0
0
7
0
0
0
0
0
14
0
0
0
0
0
% K
% Leu:
7
14
7
0
7
0
7
7
0
0
0
0
60
54
7
% L
% Met:
0
0
7
0
0
7
0
0
60
0
0
7
0
0
0
% M
% Asn:
0
20
60
0
67
0
0
7
7
7
20
7
0
14
60
% N
% Pro:
7
0
0
67
0
0
0
0
0
0
7
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
47
40
0
0
0
0
% R
% Ser:
0
0
14
0
0
7
0
40
7
0
0
0
7
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% T
% Val:
7
7
0
7
7
54
0
0
0
7
0
7
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
0
% W
% Tyr:
0
7
0
7
7
0
0
7
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _