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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBC1D16 All Species: 10.61
Human Site: T133 Identified Species: 16.67
UniProt: Q8TBP0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBP0 NP_061893.2 767 86372 T133 S P T E L R P T L T P K D E D
Chimpanzee Pan troglodytes XP_001159856 767 86325 T133 S P T E L R P T L T P K D E D
Rhesus Macaque Macaca mulatta XP_001109890 767 86411 T133 S P T E L R P T L T P K D E D
Dog Lupus familis XP_540469 762 85478 A132 S P T E P R P A L I P R D A D
Cat Felis silvestris
Mouse Mus musculus Q9CXF4 671 76509 E97 Q Q S S Y E A E W D M V T T V
Rat Rattus norvegicus XP_221188 766 86483 P132 S P T E P R P P L I P K D E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510430 604 65814 P30 G G G G G H P P A S G P D G E
Chicken Gallus gallus XP_001231439 765 86401 A132 S P T E P K G A V I L K E D I
Frog Xenopus laevis NP_001079950 727 83313 E130 R P A V I S K E D P G R D I H
Zebra Danio Brachydanio rerio XP_001921969 203 23650
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609403 702 80725 T126 C H V T I P Q T I Q E R D I R
Honey Bee Apis mellifera XP_396806 769 88817 C138 I G E K V D V C L E V K E P V
Nematode Worm Caenorhab. elegans NP_508988 744 85313 A129 Q N G Q A M P A K P A D E V K
Sea Urchin Strong. purpuratus XP_787939 808 91830 G172 R P K V G R D G G V N G A T G
Poplar Tree Populus trichocarpa XP_002308065 487 56118
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 97.9 88.7 N.A. 23.3 88.6 N.A. 58.7 78.6 71.7 20.9 N.A. 42.2 41.3 35.4 44.1
Protein Similarity: 100 99.8 98.4 92.5 N.A. 40.6 91.9 N.A. 64.5 86.6 81.2 23.3 N.A. 58.7 56.9 54.1 60.8
P-Site Identity: 100 100 100 66.6 N.A. 0 80 N.A. 13.3 33.3 13.3 0 N.A. 13.3 13.3 6.6 13.3
P-Site Similarity: 100 100 100 73.3 N.A. 6.6 80 N.A. 26.6 60 26.6 0 N.A. 33.3 33.3 20 13.3
Percent
Protein Identity: 26.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 41.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 0 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 0 7 20 7 0 7 0 7 7 0 % A
% Cys: 7 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 7 0 7 7 0 7 54 7 34 % D
% Glu: 0 0 7 40 0 7 0 14 0 7 7 0 20 27 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 14 14 7 14 0 7 7 7 0 14 7 0 7 7 % G
% His: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 7 % H
% Ile: 7 0 0 0 14 0 0 0 7 20 0 0 0 14 7 % I
% Lys: 0 0 7 7 0 7 7 0 7 0 0 40 0 0 7 % K
% Leu: 0 0 0 0 20 0 0 0 40 0 7 0 0 0 0 % L
% Met: 0 0 0 0 0 7 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 54 0 0 20 7 47 14 0 14 34 7 0 7 0 % P
% Gln: 14 7 0 7 0 0 7 0 0 7 0 0 0 0 0 % Q
% Arg: 14 0 0 0 0 40 0 0 0 0 0 20 0 0 7 % R
% Ser: 40 0 7 7 0 7 0 0 0 7 0 0 0 0 0 % S
% Thr: 0 0 40 7 0 0 0 27 0 20 0 0 7 14 0 % T
% Val: 0 0 7 14 7 0 7 0 7 7 7 7 0 7 14 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _