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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D16
All Species:
21.21
Human Site:
T189
Identified Species:
33.33
UniProt:
Q8TBP0
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP0
NP_061893.2
767
86372
T189
S
P
S
G
I
L
S
T
V
S
P
Q
D
V
T
Chimpanzee
Pan troglodytes
XP_001159856
767
86325
T189
S
P
S
G
I
L
S
T
V
S
P
Q
D
V
T
Rhesus Macaque
Macaca mulatta
XP_001109890
767
86411
T189
S
P
S
G
I
L
S
T
V
S
P
Q
D
G
T
Dog
Lupus familis
XP_540469
762
85478
A185
S
D
S
G
I
L
S
A
V
S
S
Q
D
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
G146
K
Q
S
K
E
G
M
G
W
S
Y
L
V
F
C
Rat
Rattus norvegicus
XP_221188
766
86483
T188
S
D
S
G
I
L
S
T
V
S
S
Q
D
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510430
604
65814
I79
E
L
L
G
T
T
L
I
L
A
W
V
P
N
S
Chicken
Gallus gallus
XP_001231439
765
86401
T188
S
D
S
G
I
L
S
T
I
S
S
Q
D
E
Q
Frog
Xenopus laevis
NP_001079950
727
83313
S180
S
K
D
S
T
L
D
S
D
S
D
A
F
S
S
Zebra Danio
Brachydanio rerio
XP_001921969
203
23650
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609403
702
80725
V175
K
N
N
P
I
T
S
V
N
I
T
I
S
N
P
Honey Bee
Apis mellifera
XP_396806
769
88817
Y200
N
I
N
R
Q
T
N
Y
H
R
S
D
N
L
S
Nematode Worm
Caenorhab. elegans
NP_508988
744
85313
S190
N
D
A
L
G
V
P
S
I
N
V
I
P
H
T
Sea Urchin
Strong. purpuratus
XP_787939
808
91830
P231
N
H
S
P
V
G
R
P
V
N
L
E
L
Q
T
Poplar Tree
Populus trichocarpa
XP_002308065
487
56118
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
88.7
N.A.
23.3
88.6
N.A.
58.7
78.6
71.7
20.9
N.A.
42.2
41.3
35.4
44.1
Protein Similarity:
100
99.8
98.4
92.5
N.A.
40.6
91.9
N.A.
64.5
86.6
81.2
23.3
N.A.
58.7
56.9
54.1
60.8
P-Site Identity:
100
100
93.3
73.3
N.A.
13.3
80
N.A.
6.6
66.6
20
0
N.A.
13.3
0
6.6
20
P-Site Similarity:
100
100
93.3
73.3
N.A.
13.3
80
N.A.
26.6
73.3
33.3
0
N.A.
20
40
46.6
46.6
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
7
0
7
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
27
7
0
0
0
7
0
7
0
7
7
40
0
0
% D
% Glu:
7
0
0
0
7
0
0
0
0
0
0
7
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
0
% F
% Gly:
0
0
0
47
7
14
0
7
0
0
0
0
0
20
0
% G
% His:
0
7
0
0
0
0
0
0
7
0
0
0
0
7
0
% H
% Ile:
0
7
0
0
47
0
0
7
14
7
0
14
0
0
0
% I
% Lys:
14
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
7
7
7
0
47
7
0
7
0
7
7
7
7
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
20
7
14
0
0
0
7
0
7
14
0
0
7
14
0
% N
% Pro:
0
20
0
14
0
0
7
7
0
0
20
0
14
0
7
% P
% Gln:
0
7
0
0
7
0
0
0
0
0
0
40
0
7
7
% Q
% Arg:
0
0
0
7
0
0
7
0
0
7
0
0
0
0
0
% R
% Ser:
47
0
54
7
0
0
47
14
0
54
27
0
7
7
20
% S
% Thr:
0
0
0
0
14
20
0
34
0
0
7
0
0
0
47
% T
% Val:
0
0
0
0
7
7
0
7
40
0
7
7
7
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _