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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D16
All Species:
17.88
Human Site:
T586
Identified Species:
28.1
UniProt:
Q8TBP0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP0
NP_061893.2
767
86372
T586
L
R
E
L
L
R
L
T
H
V
R
F
Y
Q
H
Chimpanzee
Pan troglodytes
XP_001159856
767
86325
T586
L
R
E
L
L
R
L
T
H
V
R
F
Y
Q
H
Rhesus Macaque
Macaca mulatta
XP_001109890
767
86411
T586
L
R
E
L
L
R
L
T
H
V
R
F
Y
Q
H
Dog
Lupus familis
XP_540469
762
85478
T581
L
R
E
L
L
R
L
T
H
L
R
F
Y
Q
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
L526
F
K
R
E
F
S
F
L
D
I
L
R
L
W
E
Rat
Rattus norvegicus
XP_221188
766
86483
T585
L
R
E
L
L
R
L
T
H
Q
R
F
Y
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510430
604
65814
A459
F
K
R
E
F
P
D
A
E
A
L
R
M
W
E
Chicken
Gallus gallus
XP_001231439
765
86401
M585
L
R
E
L
L
R
L
M
H
P
R
F
Y
Q
H
Frog
Xenopus laevis
NP_001079950
727
83313
Q564
S
L
D
E
D
G
L
Q
M
L
F
C
H
R
W
Zebra Danio
Brachydanio rerio
XP_001921969
203
23650
M57
P
D
A
E
A
L
R
M
W
E
A
C
W
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609403
702
80725
K556
I
M
L
P
H
F
Y
K
H
L
E
Q
H
N
D
Honey Bee
Apis mellifera
XP_396806
769
88817
M616
L
R
E
L
V
R
I
M
V
P
D
F
Y
A
H
Nematode Worm
Caenorhab. elegans
NP_508988
744
85313
R590
T
Y
L
R
N
M
L
R
M
F
V
P
D
F
Y
Sea Urchin
Strong. purpuratus
XP_787939
808
91830
M656
L
L
E
L
I
K
L
M
L
P
E
F
W
D
H
Poplar Tree
Populus trichocarpa
XP_002308065
487
56118
L342
M
H
S
Q
L
F
A
L
S
K
L
V
E
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
88.7
N.A.
23.3
88.6
N.A.
58.7
78.6
71.7
20.9
N.A.
42.2
41.3
35.4
44.1
Protein Similarity:
100
99.8
98.4
92.5
N.A.
40.6
91.9
N.A.
64.5
86.6
81.2
23.3
N.A.
58.7
56.9
54.1
60.8
P-Site Identity:
100
100
100
93.3
N.A.
0
93.3
N.A.
0
86.6
6.6
6.6
N.A.
6.6
53.3
6.6
40
P-Site Similarity:
100
100
100
100
N.A.
13.3
93.3
N.A.
6.6
86.6
33.3
13.3
N.A.
26.6
66.6
13.3
60
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
0
7
7
0
7
7
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
14
0
0
0
% C
% Asp:
0
7
7
0
7
0
7
0
7
0
7
0
7
7
7
% D
% Glu:
0
0
54
27
0
0
0
0
7
7
14
0
7
0
14
% E
% Phe:
14
0
0
0
14
14
7
0
0
7
7
54
0
7
0
% F
% Gly:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
0
7
0
0
0
47
0
0
0
14
0
60
% H
% Ile:
7
0
0
0
7
0
7
0
0
7
0
0
0
0
0
% I
% Lys:
0
14
0
0
0
7
0
7
0
7
0
0
0
0
0
% K
% Leu:
54
14
14
54
47
7
60
14
7
20
20
0
7
7
7
% L
% Met:
7
7
0
0
0
7
0
27
14
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
7
0
0
7
0
7
0
0
0
20
0
7
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
7
0
7
0
7
0
40
0
% Q
% Arg:
0
47
14
7
0
47
7
7
0
0
40
14
0
7
0
% R
% Ser:
7
0
7
0
0
7
0
0
7
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
7
0
0
0
7
20
7
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
14
14
7
% W
% Tyr:
0
7
0
0
0
0
7
0
0
0
0
0
47
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _