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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D16
All Species:
17.27
Human Site:
Y393
Identified Species:
27.14
UniProt:
Q8TBP0
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP0
NP_061893.2
767
86372
Y393
T
H
P
E
E
S
M
Y
K
R
L
G
V
S
A
Chimpanzee
Pan troglodytes
XP_001159856
767
86325
Y393
T
H
P
E
E
S
M
Y
K
R
L
G
V
S
A
Rhesus Macaque
Macaca mulatta
XP_001109890
767
86411
Y393
T
H
P
E
E
S
M
Y
K
R
L
G
V
S
A
Dog
Lupus familis
XP_540469
762
85478
K389
H
P
E
E
S
M
Y
K
R
L
D
V
A
A
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
K336
G
L
S
H
S
L
R
K
Q
A
W
K
F
L
L
Rat
Rattus norvegicus
XP_221188
766
86483
Y392
I
H
P
E
E
S
L
Y
R
R
L
D
V
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510430
604
65814
D269
Q
P
Q
N
G
K
R
D
E
Q
Q
K
V
L
S
Chicken
Gallus gallus
XP_001231439
765
86401
Y392
T
H
P
E
E
N
T
Y
R
R
L
D
V
S
A
Frog
Xenopus laevis
NP_001079950
727
83313
G370
L
E
H
L
N
E
G
G
Q
V
E
E
E
Y
K
Zebra Danio
Brachydanio rerio
XP_001921969
203
23650
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609403
702
80725
T366
T
T
N
F
F
Y
G
T
L
L
N
E
K
G
Q
Honey Bee
Apis mellifera
XP_396806
769
88817
P424
H
P
E
E
G
Q
V
P
M
I
T
S
L
A
W
Nematode Worm
Caenorhab. elegans
NP_508988
744
85313
E399
D
P
E
E
G
L
F
E
K
I
T
L
N
T
W
Sea Urchin
Strong. purpuratus
XP_787939
808
91830
F463
C
H
P
E
E
G
L
F
S
E
L
S
E
E
L
Poplar Tree
Populus trichocarpa
XP_002308065
487
56118
P152
M
T
L
V
W
G
K
P
R
Q
P
P
L
G
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
88.7
N.A.
23.3
88.6
N.A.
58.7
78.6
71.7
20.9
N.A.
42.2
41.3
35.4
44.1
Protein Similarity:
100
99.8
98.4
92.5
N.A.
40.6
91.9
N.A.
64.5
86.6
81.2
23.3
N.A.
58.7
56.9
54.1
60.8
P-Site Identity:
100
100
100
6.6
N.A.
0
73.3
N.A.
6.6
73.3
0
0
N.A.
6.6
6.6
13.3
33.3
P-Site Similarity:
100
100
100
20
N.A.
6.6
86.6
N.A.
26.6
86.6
6.6
0
N.A.
6.6
26.6
20
46.6
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
7
0
0
7
14
34
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
7
0
0
7
14
0
0
0
% D
% Glu:
0
7
20
60
40
7
0
7
7
7
7
14
14
7
0
% E
% Phe:
0
0
0
7
7
0
7
7
0
0
0
0
7
0
0
% F
% Gly:
7
0
0
0
20
14
14
7
0
0
0
20
0
14
0
% G
% His:
14
40
7
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
14
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
7
7
14
27
0
0
14
7
0
7
% K
% Leu:
7
7
7
7
0
14
14
0
7
14
40
7
14
14
14
% L
% Met:
7
0
0
0
0
7
20
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
7
7
7
7
0
0
0
0
7
0
7
0
0
% N
% Pro:
0
27
40
0
0
0
0
14
0
0
7
7
0
0
0
% P
% Gln:
7
0
7
0
0
7
0
0
14
14
7
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
14
0
27
34
0
0
0
0
0
% R
% Ser:
0
0
7
0
14
27
0
0
7
0
0
14
0
34
14
% S
% Thr:
34
14
0
0
0
0
7
7
0
0
14
0
0
7
0
% T
% Val:
0
0
0
7
0
0
7
0
0
7
0
7
40
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
20
% W
% Tyr:
0
0
0
0
0
7
7
34
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _