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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D16
All Species:
30
Human Site:
Y442
Identified Species:
47.14
UniProt:
Q8TBP0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP0
NP_061893.2
767
86372
Y442
W
P
F
L
L
R
Y
Y
S
H
E
S
T
S
E
Chimpanzee
Pan troglodytes
XP_001159856
767
86325
Y442
W
P
F
L
L
R
Y
Y
S
H
E
S
T
S
E
Rhesus Macaque
Macaca mulatta
XP_001109890
767
86411
Y442
W
P
F
L
L
R
Y
Y
S
H
E
S
T
S
E
Dog
Lupus familis
XP_540469
762
85478
Y437
W
P
F
L
L
R
Y
Y
S
H
E
S
T
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
N384
S
E
A
Q
E
K
R
N
S
R
L
R
D
Y
R
Rat
Rattus norvegicus
XP_221188
766
86483
Y441
W
P
F
L
L
H
Y
Y
S
H
E
S
T
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510430
604
65814
Y317
V
A
S
R
E
S
Q
Y
K
V
F
H
F
H
H
Chicken
Gallus gallus
XP_001231439
765
86401
Y441
W
P
F
L
L
R
Y
Y
S
Y
E
S
T
S
E
Frog
Xenopus laevis
NP_001079950
727
83313
H418
D
R
E
A
L
R
V
H
R
R
E
E
Y
S
Q
Zebra Danio
Brachydanio rerio
XP_001921969
203
23650
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609403
702
80725
R414
F
S
S
T
F
E
D
R
A
V
L
M
D
I
K
Honey Bee
Apis mellifera
XP_396806
769
88817
Y472
W
P
F
L
L
H
C
Y
S
Y
Q
S
T
Y
E
Nematode Worm
Caenorhab. elegans
NP_508988
744
85313
Y447
W
P
F
L
L
R
V
Y
P
W
E
S
S
A
D
Sea Urchin
Strong. purpuratus
XP_787939
808
91830
F512
W
P
F
L
L
G
F
F
A
F
D
S
T
T
E
Poplar Tree
Populus trichocarpa
XP_002308065
487
56118
L200
R
E
V
W
P
F
L
L
G
Y
H
A
Y
D
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
88.7
N.A.
23.3
88.6
N.A.
58.7
78.6
71.7
20.9
N.A.
42.2
41.3
35.4
44.1
Protein Similarity:
100
99.8
98.4
92.5
N.A.
40.6
91.9
N.A.
64.5
86.6
81.2
23.3
N.A.
58.7
56.9
54.1
60.8
P-Site Identity:
100
100
100
93.3
N.A.
6.6
93.3
N.A.
6.6
93.3
26.6
0
N.A.
0
66.6
60
53.3
P-Site Similarity:
100
100
100
100
N.A.
13.3
93.3
N.A.
6.6
100
40
0
N.A.
20
80
80
86.6
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
7
0
0
0
0
14
0
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
7
0
0
0
7
0
14
7
7
% D
% Glu:
0
14
7
0
14
7
0
0
0
0
54
7
0
0
47
% E
% Phe:
7
0
60
0
7
7
7
7
0
7
7
0
7
0
0
% F
% Gly:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
14
0
7
0
34
7
7
0
7
7
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
7
% K
% Leu:
0
0
0
60
67
0
7
7
0
0
14
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
60
0
0
7
0
0
0
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
7
0
0
0
7
0
0
0
14
% Q
% Arg:
7
7
0
7
0
47
7
7
7
14
0
7
0
0
7
% R
% Ser:
7
7
14
0
0
7
0
0
54
0
0
60
7
47
7
% S
% Thr:
0
0
0
7
0
0
0
0
0
0
0
0
54
7
0
% T
% Val:
7
0
7
0
0
0
14
0
0
14
0
0
0
0
0
% V
% Trp:
60
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
40
60
0
20
0
0
14
14
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _