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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D16
All Species:
23.33
Human Site:
Y591
Identified Species:
36.67
UniProt:
Q8TBP0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP0
NP_061893.2
767
86372
Y591
R
L
T
H
V
R
F
Y
Q
H
L
V
S
L
G
Chimpanzee
Pan troglodytes
XP_001159856
767
86325
Y591
R
L
T
H
V
R
F
Y
Q
H
L
V
S
L
G
Rhesus Macaque
Macaca mulatta
XP_001109890
767
86411
Y591
R
L
T
H
V
R
F
Y
Q
H
L
V
S
L
G
Dog
Lupus familis
XP_540469
762
85478
Y586
R
L
T
H
L
R
F
Y
Q
H
L
V
S
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
L531
S
F
L
D
I
L
R
L
W
E
V
M
W
T
E
Rat
Rattus norvegicus
XP_221188
766
86483
Y590
R
L
T
H
Q
R
F
Y
Q
H
L
V
S
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510430
604
65814
M464
P
D
A
E
A
L
R
M
W
E
A
C
W
A
H
Chicken
Gallus gallus
XP_001231439
765
86401
Y590
R
L
M
H
P
R
F
Y
Q
H
L
S
A
L
G
Frog
Xenopus laevis
NP_001079950
727
83313
H569
G
L
Q
M
L
F
C
H
R
W
I
L
L
C
F
Zebra Danio
Brachydanio rerio
XP_001921969
203
23650
W62
L
R
M
W
E
A
C
W
A
H
Y
Q
T
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609403
702
80725
H561
F
Y
K
H
L
E
Q
H
N
D
S
M
E
L
L
Honey Bee
Apis mellifera
XP_396806
769
88817
Y621
R
I
M
V
P
D
F
Y
A
H
L
Q
K
H
T
Nematode Worm
Caenorhab. elegans
NP_508988
744
85313
D595
M
L
R
M
F
V
P
D
F
Y
E
H
L
E
K
Sea Urchin
Strong. purpuratus
XP_787939
808
91830
W661
K
L
M
L
P
E
F
W
D
H
L
I
Q
I
D
Poplar Tree
Populus trichocarpa
XP_002308065
487
56118
E347
F
A
L
S
K
L
V
E
L
L
D
C
P
L
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
88.7
N.A.
23.3
88.6
N.A.
58.7
78.6
71.7
20.9
N.A.
42.2
41.3
35.4
44.1
Protein Similarity:
100
99.8
98.4
92.5
N.A.
40.6
91.9
N.A.
64.5
86.6
81.2
23.3
N.A.
58.7
56.9
54.1
60.8
P-Site Identity:
100
100
100
93.3
N.A.
0
93.3
N.A.
0
73.3
6.6
6.6
N.A.
13.3
33.3
6.6
26.6
P-Site Similarity:
100
100
100
100
N.A.
20
93.3
N.A.
0
80
40
20
N.A.
33.3
40
13.3
53.3
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
7
7
0
0
14
0
7
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
14
0
0
0
0
14
0
7
0
% C
% Asp:
0
7
0
7
0
7
0
7
7
7
7
0
0
7
7
% D
% Glu:
0
0
0
7
7
14
0
7
0
14
7
0
7
7
7
% E
% Phe:
14
7
0
0
7
7
54
0
7
0
0
0
0
0
7
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% G
% His:
0
0
0
47
0
0
0
14
0
60
0
7
0
7
14
% H
% Ile:
0
7
0
0
7
0
0
0
0
0
7
7
0
7
0
% I
% Lys:
7
0
7
0
7
0
0
0
0
0
0
0
7
0
7
% K
% Leu:
7
60
14
7
20
20
0
7
7
7
54
7
14
54
7
% L
% Met:
7
0
27
14
0
0
0
7
0
0
0
14
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% N
% Pro:
7
0
0
0
20
0
7
0
0
0
0
0
7
0
0
% P
% Gln:
0
0
7
0
7
0
7
0
40
0
0
14
7
0
0
% Q
% Arg:
47
7
7
0
0
40
14
0
7
0
0
0
0
0
0
% R
% Ser:
7
0
0
7
0
0
0
0
0
0
7
7
34
0
0
% S
% Thr:
0
0
34
0
0
0
0
0
0
0
0
0
7
7
7
% T
% Val:
0
0
0
7
20
7
7
0
0
0
7
34
0
0
0
% V
% Trp:
0
0
0
7
0
0
0
14
14
7
0
0
14
0
0
% W
% Tyr:
0
7
0
0
0
0
0
47
0
7
7
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _