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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D16
All Species:
24.55
Human Site:
Y737
Identified Species:
38.57
UniProt:
Q8TBP0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP0
NP_061893.2
767
86372
Y737
P
G
S
E
S
C
P
Y
G
G
T
V
E
M
P
Chimpanzee
Pan troglodytes
XP_001159856
767
86325
Y737
P
G
S
E
S
C
P
Y
G
G
T
V
E
I
P
Rhesus Macaque
Macaca mulatta
XP_001109890
767
86411
Y737
P
G
S
E
S
C
P
Y
G
G
T
V
E
M
P
Dog
Lupus familis
XP_540469
762
85478
Y732
P
G
S
E
S
C
P
Y
G
G
T
V
E
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
L643
S
A
F
P
S
S
T
L
P
I
L
A
A
S
E
Rat
Rattus norvegicus
XP_221188
766
86483
Y736
P
G
S
E
S
C
P
Y
G
G
T
V
E
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510430
604
65814
G576
G
E
S
C
P
Y
G
G
T
A
G
A
S
S
P
Chicken
Gallus gallus
XP_001231439
765
86401
Y736
P
A
A
E
G
C
P
Y
G
G
L
V
E
E
S
Frog
Xenopus laevis
NP_001079950
727
83313
Y698
P
E
S
E
N
C
P
Y
G
G
T
M
E
K
P
Zebra Danio
Brachydanio rerio
XP_001921969
203
23650
E174
Y
G
G
T
A
T
P
E
S
P
P
L
P
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609403
702
80725
G674
S
G
L
C
K
R
C
G
P
G
M
W
D
S
E
Honey Bee
Apis mellifera
XP_396806
769
88817
Q738
T
L
A
G
L
C
R
Q
C
G
P
G
M
W
D
Nematode Worm
Caenorhab. elegans
NP_508988
744
85313
E710
E
K
I
P
C
V
L
E
G
L
C
S
A
E
M
Sea Urchin
Strong. purpuratus
XP_787939
808
91830
E780
D
K
L
C
R
T
C
E
P
G
M
W
D
S
G
Poplar Tree
Populus trichocarpa
XP_002308065
487
56118
A459
I
C
A
G
E
N
G
A
A
H
I
P
P
G
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.9
88.7
N.A.
23.3
88.6
N.A.
58.7
78.6
71.7
20.9
N.A.
42.2
41.3
35.4
44.1
Protein Similarity:
100
99.8
98.4
92.5
N.A.
40.6
91.9
N.A.
64.5
86.6
81.2
23.3
N.A.
58.7
56.9
54.1
60.8
P-Site Identity:
100
93.3
100
93.3
N.A.
6.6
93.3
N.A.
13.3
60
73.3
20
N.A.
13.3
13.3
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
6.6
93.3
N.A.
13.3
66.6
86.6
33.3
N.A.
20
20
6.6
13.3
Percent
Protein Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
20
0
7
0
0
7
7
7
0
14
14
0
0
% A
% Cys:
0
7
0
20
7
54
14
0
7
0
7
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
0
14
0
7
% D
% Glu:
7
14
0
47
7
0
0
20
0
0
0
0
47
14
14
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
47
7
14
7
0
14
14
54
67
7
7
0
7
7
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
7
0
7
0
0
0
0
0
0
7
7
0
0
7
0
% I
% Lys:
0
14
0
0
7
0
0
0
0
0
0
0
0
7
0
% K
% Leu:
0
7
14
0
7
0
7
7
0
7
14
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
14
7
7
14
7
% M
% Asn:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
47
0
0
14
7
0
54
0
20
7
14
7
14
0
54
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
7
7
0
0
0
0
0
0
0
0
% R
% Ser:
14
0
47
0
40
7
0
0
7
0
0
7
7
34
7
% S
% Thr:
7
0
0
7
0
14
7
0
7
0
40
0
0
14
7
% T
% Val:
0
0
0
0
0
7
0
0
0
0
0
40
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
14
0
7
0
% W
% Tyr:
7
0
0
0
0
7
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _