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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM174A
All Species:
21.82
Human Site:
T181
Identified Species:
80
UniProt:
Q8TBP5
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBP5
NP_940909.1
190
19954
T181
D
D
E
D
D
D
N
T
L
F
D
A
N
H
P
Chimpanzee
Pan troglodytes
XP_517852
190
19905
T181
D
D
E
D
D
D
N
T
L
F
D
A
N
H
P
Rhesus Macaque
Macaca mulatta
XP_001097236
190
19839
T181
D
D
E
D
D
D
N
T
L
F
D
A
N
H
P
Dog
Lupus familis
XP_851027
71
8391
F64
E
D
D
D
N
T
L
F
D
A
N
H
P
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3L0
190
19967
T181
D
D
E
D
D
D
N
T
L
F
D
A
N
H
P
Rat
Rattus norvegicus
Q5FVQ7
190
20209
T181
D
D
E
D
D
D
N
T
L
F
D
A
N
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LVN1
133
14859
T126
N
D
E
E
D
D
S
T
L
F
D
V
K
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.8
37.3
N.A.
68.4
68.4
N.A.
N.A.
N.A.
N.A.
27.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
97.8
37.3
N.A.
72.6
74.2
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
N.A.
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
15
0
72
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
72
100
15
86
86
86
0
0
15
0
86
0
0
0
0
% D
% Glu:
15
0
86
15
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
0
86
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
15
0
72
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% K
% Leu:
0
0
0
0
0
0
15
0
86
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
15
0
72
0
0
0
15
0
72
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
72
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
29
% R
% Ser:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
15
0
86
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _