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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIP4K2C
All Species:
9.09
Human Site:
S314
Identified Species:
18.18
UniProt:
Q8TBX8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBX8
NP_001139731.1
421
47286
S314
S
E
V
D
G
D
C
S
L
T
G
P
P
A
L
Chimpanzee
Pan troglodytes
XP_001168018
421
47239
S314
S
E
V
D
G
D
C
S
L
T
G
P
P
A
L
Rhesus Macaque
Macaca mulatta
XP_001116157
421
47338
S314
S
E
V
D
G
D
C
S
L
T
G
P
P
A
L
Dog
Lupus familis
XP_531649
393
44442
D286
S
E
G
D
G
D
C
D
L
T
G
P
P
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91XU3
421
47317
N314
S
E
W
D
G
D
C
N
L
A
G
P
P
A
L
Rat
Rattus norvegicus
O88370
420
47030
N314
S
E
W
D
G
D
C
N
L
T
G
P
P
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510625
479
54696
E368
E
C
E
E
N
D
G
E
D
E
G
E
S
D
G
Chicken
Gallus gallus
Q5F356
405
46073
E298
E
C
E
E
N
D
G
E
D
E
G
E
S
D
G
Frog
Xenopus laevis
Q5PQ01
419
47633
N312
L
E
E
D
N
A
E
N
E
C
S
P
H
V
N
Zebra Danio
Brachydanio rerio
Q6IQE1
416
47361
N309
E
D
D
A
D
P
E
N
G
L
A
P
A
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392797
416
47916
E308
H
E
E
E
D
D
S
E
S
G
S
G
L
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY89
769
87385
A660
I
R
G
S
T
L
R
A
F
S
V
G
E
K
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
85.9
N.A.
96.1
95.4
N.A.
54.7
64.1
76.2
69.5
N.A.
N.A.
51.3
N.A.
N.A.
Protein Similarity:
100
100
99.5
88.5
N.A.
97.6
97.3
N.A.
67.2
77.9
88.5
83.3
N.A.
N.A.
67.4
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
86.6
N.A.
13.3
13.3
20
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
20
20
26.6
20
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
9
0
9
9
0
9
50
0
% A
% Cys:
0
17
0
0
0
0
50
0
0
9
0
0
0
0
0
% C
% Asp:
0
9
9
59
17
75
0
9
17
0
0
0
0
25
0
% D
% Glu:
25
67
34
25
0
0
17
25
9
17
0
17
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
50
0
17
0
9
9
67
17
0
0
17
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
9
0
0
0
0
9
0
0
50
9
0
0
9
9
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
25
0
0
34
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
67
50
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
50
0
0
9
0
0
9
25
9
9
17
0
17
0
9
% S
% Thr:
0
0
0
0
9
0
0
0
0
42
0
0
0
0
0
% T
% Val:
0
0
25
0
0
0
0
0
0
0
9
0
0
9
0
% V
% Trp:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _