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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIP4K2C All Species: 42.12
Human Site: T391 Identified Species: 84.24
UniProt: Q8TBX8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBX8 NP_001139731.1 421 47286 T391 K A A H A A K T V K H G A G A
Chimpanzee Pan troglodytes XP_001168018 421 47239 T391 K A A H A A K T V K H G A G A
Rhesus Macaque Macaca mulatta XP_001116157 421 47338 T391 K A A H A A K T V K H G A G A
Dog Lupus familis XP_531649 393 44442 T363 K A A H A A K T V K H G A G A
Cat Felis silvestris
Mouse Mus musculus Q91XU3 421 47317 T391 K A A H A A K T V K H G A G A
Rat Rattus norvegicus O88370 420 47030 V391 A A H A A K T V K H G A G A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510625 479 54696 T445 K A A H A A K T V K H G A G A
Chicken Gallus gallus Q5F356 405 46073 T375 K A A H A A K T V K H G A G A
Frog Xenopus laevis Q5PQ01 419 47633 T389 K A A H A A K T V K H G A G A
Zebra Danio Brachydanio rerio Q6IQE1 416 47361 T386 K A A H A A K T V K H G A G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392797 416 47916 T385 Q A A K A A K T V K Y G A N V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RY89 769 87385 S737 K V E H T C K S M K Y D P M T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99 85.9 N.A. 96.1 95.4 N.A. 54.7 64.1 76.2 69.5 N.A. N.A. 51.3 N.A. N.A.
Protein Similarity: 100 100 99.5 88.5 N.A. 97.6 97.3 N.A. 67.2 77.9 88.5 83.3 N.A. N.A. 67.4 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 100 100 100 100 N.A. N.A. 66.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 100 100 100 100 N.A. N.A. 80 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 33.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 92 84 9 92 84 0 0 0 0 0 9 84 9 75 % A
% Cys: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 9 84 9 75 0 % G
% His: 0 0 9 84 0 0 0 0 0 9 75 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 84 0 0 9 0 9 92 0 9 92 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 9 0 9 84 0 0 0 0 0 0 9 % T
% Val: 0 9 0 0 0 0 0 9 84 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _