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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RBM46
All Species:
14.55
Human Site:
S246
Identified Species:
29.09
UniProt:
Q8TBY0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBY0
NP_659416.1
533
60023
S246
Y
V
R
N
L
M
I
S
T
T
E
E
T
I
K
Chimpanzee
Pan troglodytes
XP_528865
470
53214
E192
G
F
A
F
V
E
Y
E
S
H
R
A
A
A
M
Rhesus Macaque
Macaca mulatta
XP_001092238
431
48959
E153
G
F
A
F
V
E
Y
E
S
H
R
A
A
A
M
Dog
Lupus familis
XP_532699
533
60112
S246
Y
V
R
N
L
M
I
S
T
T
E
E
T
I
K
Cat
Felis silvestris
Mouse
Mus musculus
P86049
533
60059
S246
Y
V
R
N
L
M
I
S
T
T
E
E
T
I
K
Rat
Rattus norvegicus
Q66H68
590
64076
E256
Y
V
R
N
L
M
I
E
T
T
E
E
T
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518200
607
68030
E290
F
I
G
A
I
P
K
E
K
K
K
E
E
I
L
Chicken
Gallus gallus
XP_420372
491
55527
T208
R
R
R
L
L
P
G
T
F
Q
L
W
G
R
A
Frog
Xenopus laevis
Q6DCB7
371
41395
L93
Q
D
I
Y
E
D
K
L
I
P
L
F
Q
S
V
Zebra Danio
Brachydanio rerio
Q08BH5
510
56941
S230
Y
V
R
N
L
M
L
S
T
T
E
E
T
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781163
595
65764
H243
Y
V
R
N
L
M
L
H
T
T
E
E
T
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q05196
668
73191
E235
Y
V
K
N
L
P
K
E
I
T
D
D
E
L
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.9
80.1
98.5
N.A.
96.4
46
N.A.
70.8
71.8
29.6
62.4
N.A.
N.A.
N.A.
N.A.
46.8
Protein Similarity:
100
87.9
80.6
98.8
N.A.
98.1
58.4
N.A.
73.4
81.2
43.5
75.4
N.A.
N.A.
N.A.
N.A.
59.3
P-Site Identity:
100
0
0
100
N.A.
100
93.3
N.A.
13.3
13.3
0
80
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
13.3
13.3
100
N.A.
100
93.3
N.A.
40
20
0
100
N.A.
N.A.
N.A.
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
9
0
0
0
0
0
0
0
17
17
17
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
9
0
0
0
0
9
9
0
0
0
% D
% Glu:
0
0
0
0
9
17
0
42
0
0
50
59
17
0
0
% E
% Phe:
9
17
0
17
0
0
0
0
9
0
0
9
0
0
0
% F
% Gly:
17
0
9
0
0
0
9
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
17
0
0
0
0
0
% H
% Ile:
0
9
9
0
9
0
34
0
17
0
0
0
0
50
0
% I
% Lys:
0
0
9
0
0
0
25
0
9
9
9
0
0
0
42
% K
% Leu:
0
0
0
9
67
0
17
9
0
0
17
0
0
17
9
% L
% Met:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
17
% M
% Asn:
0
0
0
59
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
25
0
0
0
9
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% Q
% Arg:
9
9
59
0
0
0
0
0
0
0
17
0
0
9
9
% R
% Ser:
0
0
0
0
0
0
0
34
17
0
0
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
0
9
50
59
0
0
50
0
0
% T
% Val:
0
59
0
0
17
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
59
0
0
9
0
0
17
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _