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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBM46 All Species: 13.64
Human Site: S475 Identified Species: 27.27
UniProt: Q8TBY0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBY0 NP_659416.1 533 60023 S475 D Y N F H R S S I N S L S P V
Chimpanzee Pan troglodytes XP_528865 470 53214 Y413 N W A P P E Y Y L Y S T T S Q
Rhesus Macaque Macaca mulatta XP_001092238 431 48959 Y374 N W A P P E Y Y L Y S T T S Q
Dog Lupus familis XP_532699 533 60112 S475 D Y T F R R S S I N S L S P V
Cat Felis silvestris
Mouse Mus musculus P86049 533 60059 S475 D F N F R R S S I N S L S P V
Rat Rattus norvegicus Q66H68 590 64076 Q485 M I S P I A V Q P D P A T A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518200 607 68030 I521 P G T K L T P I S M Y S L K W
Chicken Gallus gallus XP_420372 491 55527 K429 G K I H L V C K V L I P S I A
Frog Xenopus laevis Q6DCB7 371 41395 V314 I R F W Y Q V V I P T Y P T P
Zebra Danio Brachydanio rerio Q08BH5 510 56941 S453 L W N L D C S S G S S L N V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781163 595 65764 E515 G V P V D G D E S Q S D S P V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q05196 668 73191 F475 G Y G Y Q V Q F M P G M R P G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.9 80.1 98.5 N.A. 96.4 46 N.A. 70.8 71.8 29.6 62.4 N.A. N.A. N.A. N.A. 46.8
Protein Similarity: 100 87.9 80.6 98.8 N.A. 98.1 58.4 N.A. 73.4 81.2 43.5 75.4 N.A. N.A. N.A. N.A. 59.3
P-Site Identity: 100 6.6 6.6 86.6 N.A. 86.6 0 N.A. 0 6.6 6.6 33.3 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 33.3 33.3 86.6 N.A. 93.3 20 N.A. 0 13.3 33.3 53.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 21.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 36.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 9 0 0 0 0 0 9 0 9 17 % A
% Cys: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % C
% Asp: 25 0 0 0 17 0 9 0 0 9 0 9 0 0 0 % D
% Glu: 0 0 0 0 0 17 0 9 0 0 0 0 0 0 0 % E
% Phe: 0 9 9 25 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 25 9 9 0 0 9 0 0 9 0 9 0 0 0 9 % G
% His: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 9 0 9 0 0 9 34 0 9 0 0 9 0 % I
% Lys: 0 9 0 9 0 0 0 9 0 0 0 0 0 9 0 % K
% Leu: 9 0 0 9 17 0 0 0 17 9 0 34 9 0 0 % L
% Met: 9 0 0 0 0 0 0 0 9 9 0 9 0 0 0 % M
% Asn: 17 0 25 0 0 0 0 0 0 25 0 0 9 0 0 % N
% Pro: 9 0 9 25 17 0 9 0 9 17 9 9 9 42 9 % P
% Gln: 0 0 0 0 9 9 9 9 0 9 0 0 0 0 17 % Q
% Arg: 0 9 0 0 17 25 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 0 9 0 0 0 34 34 17 9 59 9 42 17 9 % S
% Thr: 0 0 17 0 0 9 0 0 0 0 9 17 25 9 0 % T
% Val: 0 9 0 9 0 17 17 9 9 0 0 0 0 9 34 % V
% Trp: 0 25 0 9 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 25 0 9 9 0 17 17 0 17 9 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _