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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR66
All Species:
7.27
Human Site:
S1146
Identified Species:
22.86
UniProt:
Q8TBY9
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBY9
NP_653269.3
1154
130645
S1146
E
I
L
G
L
T
I
S
E
D
S
G
Q
D
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534664
1163
132490
S1147
D
I
L
G
L
T
I
S
Q
D
F
R
Q
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
XP_001079344
1256
140835
S1128
E
I
L
G
L
T
L
S
N
H
S
E
Q
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506270
1113
125384
M1106
S
I
P
E
E
D
P
M
V
P
E
G
Q
G
W
Chicken
Gallus gallus
XP_415147
988
109326
E981
I
L
G
L
S
I
A
E
P
E
K
R
A
V
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697723
906
101629
F899
L
L
Q
A
R
G
K
F
F
I
F
K
D
C
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397134
662
76259
T655
G
I
E
F
P
E
E
T
R
A
D
D
D
L
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785437
1181
130214
A1170
E
L
L
G
F
G
G
A
A
E
P
S
E
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
79.7
N.A.
N.A.
63.9
N.A.
59.6
45.9
N.A.
38.2
N.A.
N.A.
22.3
N.A.
41.1
Protein Similarity:
100
N.A.
N.A.
87.7
N.A.
N.A.
75.8
N.A.
74
61.2
N.A.
54.5
N.A.
N.A.
35.5
N.A.
59.7
P-Site Identity:
100
N.A.
N.A.
66.6
N.A.
N.A.
60
N.A.
20
0
N.A.
0
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
100
N.A.
N.A.
80
N.A.
N.A.
66.6
N.A.
20
13.3
N.A.
6.6
N.A.
N.A.
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
13
13
13
13
0
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% C
% Asp:
13
0
0
0
0
13
0
0
0
25
13
13
25
25
13
% D
% Glu:
38
0
13
13
13
13
13
13
13
25
13
13
13
0
0
% E
% Phe:
0
0
0
13
13
0
0
13
13
0
25
0
0
0
0
% F
% Gly:
13
0
13
50
0
25
13
0
0
0
0
25
0
25
13
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
13
63
0
0
0
13
25
0
0
13
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
13
0
0
0
13
13
0
0
13
% K
% Leu:
13
38
50
13
38
0
13
0
0
0
0
0
0
13
0
% L
% Met:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
25
% N
% Pro:
0
0
13
0
13
0
13
0
13
13
13
0
0
0
13
% P
% Gln:
0
0
13
0
0
0
0
0
13
0
0
0
50
0
0
% Q
% Arg:
0
0
0
0
13
0
0
0
13
0
0
25
0
0
0
% R
% Ser:
13
0
0
0
13
0
0
38
0
0
25
13
0
13
0
% S
% Thr:
0
0
0
0
0
38
0
13
0
0
0
0
0
0
13
% T
% Val:
0
0
0
0
0
0
0
0
13
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _