KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR66
All Species:
5.76
Human Site:
Y426
Identified Species:
18.1
UniProt:
Q8TBY9
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBY9
NP_653269.3
1154
130645
Y426
S
K
T
R
A
I
Y
Y
A
W
Y
E
E
R
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534664
1163
132490
Y427
S
K
T
Q
A
I
Y
Y
V
W
Y
E
E
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
XP_001079344
1256
140835
T409
A
P
L
L
T
E
K
T
F
N
K
L
V
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506270
1113
125384
T400
E
Y
S
A
P
C
L
T
E
K
T
F
N
K
I
Chicken
Gallus gallus
XP_415147
988
109326
T275
R
Q
G
A
D
R
R
T
S
T
D
P
P
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697723
906
101629
G193
Y
L
V
T
V
G
A
G
L
V
Q
R
V
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397134
662
76259
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785437
1181
130214
K403
P
T
Q
V
I
F
Y
K
W
G
G
E
K
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
79.7
N.A.
N.A.
63.9
N.A.
59.6
45.9
N.A.
38.2
N.A.
N.A.
22.3
N.A.
41.1
Protein Similarity:
100
N.A.
N.A.
87.7
N.A.
N.A.
75.8
N.A.
74
61.2
N.A.
54.5
N.A.
N.A.
35.5
N.A.
59.7
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
N.A.
0
N.A.
0
0
N.A.
0
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
N.A.
6.6
N.A.
13.3
13.3
N.A.
0
N.A.
N.A.
0
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
25
25
0
13
0
13
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
13
0
0
0
0
0
0
0
13
0
% C
% Asp:
0
0
0
0
13
0
0
0
0
0
13
0
0
0
25
% D
% Glu:
13
0
0
0
0
13
0
0
13
0
0
38
25
0
13
% E
% Phe:
0
0
0
0
0
13
0
0
13
0
0
13
0
0
0
% F
% Gly:
0
0
13
0
0
13
0
13
0
13
13
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
25
0
0
0
0
0
0
0
13
25
% I
% Lys:
0
25
0
0
0
0
13
13
0
13
13
0
13
13
13
% K
% Leu:
0
13
13
13
0
0
13
0
13
0
0
13
0
13
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
13
0
0
13
0
0
% N
% Pro:
13
13
0
0
13
0
0
0
0
0
0
13
13
0
0
% P
% Gln:
0
13
13
13
0
0
0
0
0
0
13
0
0
0
0
% Q
% Arg:
13
0
0
13
0
13
13
0
0
0
0
13
0
25
0
% R
% Ser:
25
0
13
0
0
0
0
0
13
0
0
0
0
0
0
% S
% Thr:
0
13
25
13
13
0
0
38
0
13
13
0
0
0
0
% T
% Val:
0
0
13
13
13
0
0
0
13
13
0
0
25
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
13
25
0
0
0
0
0
% W
% Tyr:
13
13
0
0
0
0
38
25
0
0
25
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _