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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC110 All Species: 12.73
Human Site: Y380 Identified Species: 31.11
UniProt: Q8TBZ0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBZ0 NP_001138883.1 833 96726 Y380 F H S R V P R Y T L S F L D Q
Chimpanzee Pan troglodytes XP_001163267 833 96790 Y380 F H S R V P R Y T L S F L D Q
Rhesus Macaque Macaca mulatta XP_001086283 832 96497 Y379 F H S R V P R Y T L S F L D Q
Dog Lupus familis XP_532840 843 98082 H389 F H S G V P R H T L S F F D P
Cat Felis silvestris
Mouse Mus musculus Q3V125 848 96337 Y386 F H S R A P R Y T L S V L D L
Rat Rattus norvegicus XP_214351 800 92050 L353 P R H T L S V L D P G K H K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518572 781 87737 G334 I P A E D H L G G F P L S C Q
Chicken Gallus gallus XP_426333 415 48436
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJL0 1241 141112 A574 I D A K Y D V A I S T A C A G
Baker's Yeast Sacchar. cerevisiae Q02455 1875 218438 G1069 E Q L H T Y K G Q V K T L N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 93.5 76.5 N.A. 67.5 63.8 N.A. 39.5 20.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 96.4 85.8 N.A. 79.9 76.8 N.A. 58.3 34.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 73.3 N.A. 80 0 N.A. 6.6 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 80 6.6 N.A. 13.3 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. 38.4 34 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 10 0 0 10 0 0 0 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % C
% Asp: 0 10 0 0 10 10 0 0 10 0 0 0 0 50 0 % D
% Glu: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 50 0 0 0 0 0 0 0 0 10 0 40 10 0 0 % F
% Gly: 0 0 0 10 0 0 0 20 10 0 10 0 0 0 10 % G
% His: 0 50 10 10 0 10 0 10 0 0 0 0 10 0 0 % H
% Ile: 20 0 0 0 0 0 0 0 10 0 0 0 0 0 10 % I
% Lys: 0 0 0 10 0 0 10 0 0 0 10 10 0 10 0 % K
% Leu: 0 0 10 0 10 0 10 10 0 50 0 10 50 0 20 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 10 10 0 0 0 50 0 0 0 10 10 0 0 0 10 % P
% Gln: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 40 % Q
% Arg: 0 10 0 40 0 0 50 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 50 0 0 10 0 0 0 10 50 0 10 0 0 % S
% Thr: 0 0 0 10 10 0 0 0 50 0 10 10 0 0 0 % T
% Val: 0 0 0 0 40 0 20 0 0 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 10 0 40 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _