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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RG9MTD2 All Species: 22.73
Human Site: Y185 Identified Species: 45.45
UniProt: Q8TBZ6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBZ6 NP_001128137.1 339 39719 Y185 I K K E D L I Y L T S D S P N
Chimpanzee Pan troglodytes XP_001167239 339 39690 Y185 I K K E D L I Y L T S D S P N
Rhesus Macaque Macaca mulatta XP_001107346 339 39693 Y185 I K K E D L I Y L T S D S P N
Dog Lupus familis XP_544994 339 39727 Y185 I K K E D L I Y L T S D S P N
Cat Felis silvestris
Mouse Mus musculus Q8C1Z8 328 37947 S174 H I K S E H Y S E L I K K E D
Rat Rattus norvegicus Q4KLI2 335 38406 Y185 I K K E D L V Y L T S D S P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q08BM0 310 35561 Q159 H V F L T E L Q E D S L L Y K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VR56 319 36423 E157 F K K N E G W E N W H V Q Y Y
Honey Bee Apis mellifera XP_625003 254 29732 L104 Q I L R C Y T L N R R A I A P
Nematode Worm Caenorhab. elegans NP_001122773 296 34536 N145 I Y D G N E H N L N Q D I H L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001169699 371 41498 Y187 D R K E N L V Y L T A D A E T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12400 293 34502 R143 K V A P F D K R L K Q R F E T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 96.4 89.3 N.A. 76.1 74.3 N.A. N.A. N.A. N.A. 25.9 N.A. 28.6 33 34.5 N.A.
Protein Similarity: 100 99.7 97 96.1 N.A. 85.8 84.9 N.A. N.A. N.A. N.A. 46 N.A. 48.3 48.9 51.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 6.6 93.3 N.A. N.A. N.A. N.A. 6.6 N.A. 13.3 0 20 N.A.
P-Site Similarity: 100 100 100 100 N.A. 20 100 N.A. N.A. N.A. N.A. 13.3 N.A. 20 0 26.6 N.A.
Percent
Protein Identity: N.A. 29.6 N.A. N.A. 26.2 N.A.
Protein Similarity: N.A. 51.2 N.A. N.A. 47.2 N.A.
P-Site Identity: N.A. 46.6 N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. 80 N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 0 0 9 9 9 9 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 0 42 9 0 0 0 9 0 59 0 0 9 % D
% Glu: 0 0 0 50 17 17 0 9 17 0 0 0 0 25 0 % E
% Phe: 9 0 9 0 9 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % G
% His: 17 0 0 0 0 9 9 0 0 0 9 0 0 9 0 % H
% Ile: 50 17 0 0 0 0 34 0 0 0 9 0 17 0 0 % I
% Lys: 9 50 67 0 0 0 9 0 0 9 0 9 9 0 9 % K
% Leu: 0 0 9 9 0 50 9 9 67 9 0 9 9 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 17 0 0 9 17 9 0 0 0 0 42 % N
% Pro: 0 0 0 9 0 0 0 0 0 0 0 0 0 42 9 % P
% Gln: 9 0 0 0 0 0 0 9 0 0 17 0 9 0 0 % Q
% Arg: 0 9 0 9 0 0 0 9 0 9 9 9 0 0 0 % R
% Ser: 0 0 0 9 0 0 0 9 0 0 50 0 42 0 0 % S
% Thr: 0 0 0 0 9 0 9 0 0 50 0 0 0 0 17 % T
% Val: 0 17 0 0 0 0 17 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 9 9 50 0 0 0 0 0 17 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _