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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MDM1
All Species:
26.67
Human Site:
S306
Identified Species:
65.19
UniProt:
Q8TC05
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC05
NP_064513.1
714
80735
S306
Q
R
L
G
K
V
N
S
E
Y
R
A
K
F
L
Chimpanzee
Pan troglodytes
XP_509206
714
80684
S306
Q
R
L
G
K
V
N
S
E
Y
R
A
K
F
L
Rhesus Macaque
Macaca mulatta
XP_001117173
720
81656
S307
Q
R
L
G
K
V
N
S
E
Y
R
A
K
F
L
Dog
Lupus familis
XP_531669
782
87790
S375
Q
R
L
G
K
V
N
S
E
Y
R
A
K
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D067
708
79671
S307
Q
R
L
G
K
V
N
S
E
Y
R
A
K
F
L
Rat
Rattus norvegicus
Q5PQN4
719
80679
S306
Q
R
L
G
K
V
N
S
E
Y
R
A
K
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511246
686
76752
G298
A
L
Y
F
Y
Q
D
G
A
W
I
R
A
K
G
Chicken
Gallus gallus
Q5ZMW6
691
77332
S290
S
K
V
P
N
Q
A
S
Q
N
P
L
N
S
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RHU7
656
74275
R287
D
P
S
P
K
V
M
R
K
G
K
T
E
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799039
812
89995
S339
A
T
V
R
K
W
R
S
E
Y
K
S
N
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
94.4
73.7
N.A.
70.3
68.5
N.A.
50.4
44.5
N.A.
36.4
N.A.
N.A.
N.A.
N.A.
21.1
Protein Similarity:
100
99.3
96.3
81.1
N.A.
79.4
77.7
N.A.
64.4
60.3
N.A.
52.9
N.A.
N.A.
N.A.
N.A.
37.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
33.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
0
0
0
0
10
0
10
0
0
60
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
70
0
0
0
10
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
70
0
% F
% Gly:
0
0
0
60
0
0
0
10
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
10
0
0
80
0
0
0
10
0
20
0
60
10
10
% K
% Leu:
0
10
60
0
0
0
0
0
0
0
0
10
0
0
60
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
10
0
60
0
0
10
0
0
20
0
0
% N
% Pro:
0
10
0
20
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
60
0
0
0
0
20
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
60
0
10
0
0
10
10
0
0
60
10
0
0
10
% R
% Ser:
10
0
10
0
0
0
0
80
0
0
0
10
0
10
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
20
0
0
70
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
0
0
0
70
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _