KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MDM1
All Species:
7.27
Human Site:
S601
Identified Species:
17.78
UniProt:
Q8TC05
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC05
NP_064513.1
714
80735
S601
P
L
P
L
R
E
D
S
E
D
N
I
H
K
F
Chimpanzee
Pan troglodytes
XP_509206
714
80684
F601
P
L
P
L
R
E
D
F
E
D
N
I
H
K
F
Rhesus Macaque
Macaca mulatta
XP_001117173
720
81656
S607
P
L
P
L
R
E
D
S
E
D
N
I
P
R
F
Dog
Lupus familis
XP_531669
782
87790
S668
P
L
P
L
R
E
D
S
E
A
N
H
I
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D067
708
79671
D597
D
P
L
P
L
R
E
D
C
E
A
N
V
L
R
Rat
Rattus norvegicus
Q5PQN4
719
80679
C608
P
L
P
L
R
Q
D
C
D
A
N
V
L
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511246
686
76752
E588
L
P
L
R
E
D
V
E
A
P
R
Y
A
E
A
Chicken
Gallus gallus
Q5ZMW6
691
77332
Q576
P
L
P
L
R
Q
D
Q
W
H
P
N
G
V
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RHU7
656
74275
K563
Y
R
S
L
K
P
P
K
P
S
R
K
Q
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799039
812
89995
G699
R
F
F
E
T
S
P
G
M
P
T
I
P
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
94.4
73.7
N.A.
70.3
68.5
N.A.
50.4
44.5
N.A.
36.4
N.A.
N.A.
N.A.
N.A.
21.1
Protein Similarity:
100
99.3
96.3
81.1
N.A.
79.4
77.7
N.A.
64.4
60.3
N.A.
52.9
N.A.
N.A.
N.A.
N.A.
37.5
P-Site Identity:
100
93.3
86.6
66.6
N.A.
0
46.6
N.A.
0
40
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
66.6
N.A.
13.3
73.3
N.A.
13.3
46.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
20
10
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
10
60
10
10
30
0
0
0
0
0
% D
% Glu:
0
0
0
10
10
40
10
10
40
10
0
0
0
10
0
% E
% Phe:
0
10
10
0
0
0
0
10
0
0
0
0
0
0
30
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
10
20
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
40
10
0
0
% I
% Lys:
0
0
0
0
10
0
0
10
0
0
0
10
0
20
20
% K
% Leu:
10
60
20
70
10
0
0
0
0
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
50
20
0
10
0
% N
% Pro:
60
20
60
10
0
10
20
0
10
20
10
0
20
10
0
% P
% Gln:
0
0
0
0
0
20
0
10
0
0
0
0
10
10
0
% Q
% Arg:
10
10
0
10
60
10
0
0
0
0
20
0
0
20
10
% R
% Ser:
0
0
10
0
0
10
0
30
0
10
0
0
0
0
20
% S
% Thr:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
10
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _