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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MDM1
All Species:
21.52
Human Site:
T515
Identified Species:
52.59
UniProt:
Q8TC05
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC05
NP_064513.1
714
80735
T515
E
K
G
G
R
L
P
T
P
K
L
R
E
L
G
Chimpanzee
Pan troglodytes
XP_509206
714
80684
T515
E
K
G
G
R
L
P
T
P
K
L
R
E
L
G
Rhesus Macaque
Macaca mulatta
XP_001117173
720
81656
T521
E
K
G
G
R
L
P
T
P
K
L
R
E
L
G
Dog
Lupus familis
XP_531669
782
87790
T582
G
K
E
G
R
L
P
T
P
K
L
R
E
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D067
708
79671
P511
S
G
K
G
G
R
L
P
T
P
R
L
R
E
L
Rat
Rattus norvegicus
Q5PQN4
719
80679
T522
G
K
G
G
R
L
P
T
P
R
L
R
E
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511246
686
76752
T502
G
K
G
G
R
L
P
T
P
K
L
K
E
L
G
Chicken
Gallus gallus
Q5ZMW6
691
77332
A490
K
L
R
A
L
G
R
A
Q
R
T
H
H
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RHU7
656
74275
E477
E
S
L
S
S
A
E
E
G
S
E
A
S
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799039
812
89995
I613
S
A
P
V
K
A
I
I
P
G
G
I
T
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
94.4
73.7
N.A.
70.3
68.5
N.A.
50.4
44.5
N.A.
36.4
N.A.
N.A.
N.A.
N.A.
21.1
Protein Similarity:
100
99.3
96.3
81.1
N.A.
79.4
77.7
N.A.
64.4
60.3
N.A.
52.9
N.A.
N.A.
N.A.
N.A.
37.5
P-Site Identity:
100
100
100
86.6
N.A.
6.6
86.6
N.A.
86.6
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
6.6
93.3
N.A.
93.3
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
20
0
10
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
40
0
10
0
0
0
10
10
0
0
10
0
60
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
30
10
50
70
10
10
0
0
10
10
10
0
0
0
70
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% H
% Ile:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
0
% I
% Lys:
10
60
10
0
10
0
0
0
0
50
0
10
0
10
0
% K
% Leu:
0
10
10
0
10
60
10
0
0
0
60
10
0
60
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
10
0
0
0
60
10
70
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
60
10
10
0
0
20
10
50
10
0
0
% R
% Ser:
20
10
0
10
10
0
0
0
0
10
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
60
10
0
10
0
10
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _