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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBC1D15 All Species: 17.88
Human Site: S348 Identified Species: 39.33
UniProt: Q8TC07 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TC07 NP_001139686.1 691 79491 S348 M I F R G G L S H A L R K Q A
Chimpanzee Pan troglodytes XP_001159417 691 79464 S348 M I F R G G L S H A L R K Q A
Rhesus Macaque Macaca mulatta XP_001117529 687 78931 S348 M I F R G G L S H A L R K Q A
Dog Lupus familis XP_531681 882 99341 S539 M I F R G G L S H A L R K Q A
Cat Felis silvestris
Mouse Mus musculus Q9CXF4 671 76509 S331 K I F R G G L S H S L R K Q A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512516 918 104718 C456 K I F R G G L C H A V R K Q A
Chicken Gallus gallus NP_001012827 667 76877 C329 S I F K G G L C H T L R K E A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001166096 664 76835 C326 A I F K G G L C H A V R K E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624756 650 75094 W318 F L L N Y Y P W N S T H I E R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190499 1259 155020 M65 V Q Y K R I L M R V Q Y K R I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P48365 746 87287 N387 I F H G G L E N D S L R G K V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 93.7 74.8 N.A. 89 N.A. N.A. 63.8 79 N.A. 61.3 N.A. N.A. 37.9 N.A. 26.2
Protein Similarity: 100 99.8 95 76.4 N.A. 92.4 N.A. N.A. 69.1 86.4 N.A. 75.9 N.A. N.A. 53.6 N.A. 37
P-Site Identity: 100 100 100 100 N.A. 86.6 N.A. N.A. 80 66.6 N.A. 66.6 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 86.6 80 N.A. 86.6 N.A. N.A. 26.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 55 0 0 0 0 73 % A
% Cys: 0 0 0 0 0 0 0 28 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 0 28 0 % E
% Phe: 10 10 73 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 82 73 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 10 0 0 0 0 0 73 0 0 10 0 0 0 % H
% Ile: 10 73 0 0 0 10 0 0 0 0 0 0 10 0 10 % I
% Lys: 19 0 0 28 0 0 0 0 0 0 0 0 82 10 0 % K
% Leu: 0 10 10 0 0 10 82 0 0 0 64 0 0 0 0 % L
% Met: 37 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 10 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 10 0 0 55 0 % Q
% Arg: 0 0 0 55 10 0 0 0 10 0 0 82 0 10 10 % R
% Ser: 10 0 0 0 0 0 0 46 0 28 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 10 19 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 10 10 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _