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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D15
All Species:
16.36
Human Site:
T689
Identified Species:
36
UniProt:
Q8TC07
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC07
NP_001139686.1
691
79491
T689
S
S
D
V
C
R
L
T
P
A
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_001159417
691
79464
T689
S
S
D
V
C
R
L
T
P
A
_
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001117529
687
78931
T685
S
S
D
V
C
R
L
T
P
A
_
_
_
_
_
Dog
Lupus familis
XP_531681
882
99341
T880
S
P
N
V
S
R
L
T
P
A
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXF4
671
76509
T669
S
P
N
A
C
R
L
T
P
A
_
_
_
_
_
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512516
918
104718
R797
L
C
D
S
I
R
F
R
V
E
F
M
S
G
S
Chicken
Gallus gallus
NP_001012827
667
76877
A665
M
S
E
T
Q
S
L
A
P
A
_
_
_
_
_
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001166096
664
76835
V660
T
T
Q
N
G
C
K
V
A
F
I
S
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624756
650
75094
E647
L
S
Y
I
A
V
N
E
T
N
K
_
_
_
_
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190499
1259
155020
I1226
P
S
M
M
R
E
I
I
G
L
E
D
R
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P48365
746
87287
I734
L
L
S
K
K
P
I
I
R
H
E
G
Q
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
93.7
74.8
N.A.
89
N.A.
N.A.
63.8
79
N.A.
61.3
N.A.
N.A.
37.9
N.A.
26.2
Protein Similarity:
100
99.8
95
76.4
N.A.
92.4
N.A.
N.A.
69.1
86.4
N.A.
75.9
N.A.
N.A.
53.6
N.A.
37
P-Site Identity:
100
100
100
70
N.A.
70
N.A.
N.A.
13.3
40
N.A.
0
N.A.
N.A.
9
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
80
N.A.
N.A.
20
50
N.A.
25
N.A.
N.A.
18.1
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
10
10
55
0
0
0
0
0
% A
% Cys:
0
10
0
0
37
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
37
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
10
0
0
10
0
10
0
10
19
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
10
10
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
10
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
19
19
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
10
0
0
0
10
0
0
0
0
% K
% Leu:
28
10
0
0
0
0
55
0
0
10
0
0
0
0
0
% L
% Met:
10
0
10
10
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
19
10
0
0
10
0
0
10
0
0
0
10
0
% N
% Pro:
10
19
0
0
0
10
0
0
55
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
10
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
10
55
0
10
10
0
0
0
10
10
10
% R
% Ser:
46
55
10
10
10
10
0
0
0
0
0
10
10
0
19
% S
% Thr:
10
10
0
10
0
0
0
46
10
0
0
0
0
0
0
% T
% Val:
0
0
0
37
0
10
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
55
64
73
73
73
% _