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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RDH11 All Species: 33.64
Human Site: S106 Identified Species: 56.92
UniProt: Q8TC12 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TC12 NP_057110.3 318 35386 S106 L D L S D T K S I R A F A K G
Chimpanzee Pan troglodytes XP_510021 635 69387 H94 G F L A E E K H L H V L I N N
Rhesus Macaque Macaca mulatta XP_001107838 318 35380 S106 L D L S D T K S I R A F A K G
Dog Lupus familis XP_854354 337 37237 S125 L D L A D T K S I R A F A K G
Cat Felis silvestris
Mouse Mus musculus Q9QYF1 316 35129 S103 L D L A D T K S I R A F A K D
Rat Rattus norvegicus NP_001012193 316 35103 S103 L D L A D T K S I R A F A E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521365 217 24366 V29 I L I N N A G V M M C P Y S K
Chicken Gallus gallus Q5F389 414 46711 S189 L D L A S L R S V Q N F A E A
Frog Xenopus laevis NP_001085680 329 36102 S103 L D L A S S K S I K E F A K T
Zebra Danio Brachydanio rerio Q803A8 412 46303 S186 L D L A S L R S V R Q F A E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLU5 409 46492 S188 L D L S S L R S V Q R F V E E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798545 322 35072 G100 K I S S D E E G V D V L V N N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42536 405 43844 S156 L D L A S L D S V R Q F V D N
Baker's Yeast Sacchar. cerevisiae Q08651 330 37466 C103 L D L T D L K C V E R A A L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.3 97.8 81.3 N.A. 84.9 82.6 N.A. 51.2 32.6 46.8 30.1 N.A. 28.1 N.A. N.A. 47.2
Protein Similarity: 100 43.1 99 87.8 N.A. 91.1 91.5 N.A. 59.7 45.8 63.8 45.3 N.A. 46.2 N.A. N.A. 67
P-Site Identity: 100 13.3 100 93.3 N.A. 86.6 86.6 N.A. 0 40 60 46.6 N.A. 40 N.A. N.A. 13.3
P-Site Similarity: 100 33.3 100 100 N.A. 93.3 100 N.A. 33.3 73.3 80 73.3 N.A. 66.6 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 29.6 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. 44.4 42.1 N.A.
P-Site Identity: N.A. N.A. N.A. 40 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 58 0 8 0 0 0 0 36 8 65 0 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % C
% Asp: 0 79 0 0 50 0 8 0 0 8 0 0 0 8 8 % D
% Glu: 0 0 0 0 8 15 8 0 0 8 8 0 0 29 8 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 72 0 0 0 % F
% Gly: 8 0 0 0 0 0 8 8 0 0 0 0 0 0 29 % G
% His: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % H
% Ile: 8 8 8 0 0 0 0 0 43 0 0 0 8 0 0 % I
% Lys: 8 0 0 0 0 0 58 0 0 8 0 0 0 36 15 % K
% Leu: 79 8 86 0 0 36 0 0 8 0 0 15 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % M
% Asn: 0 0 0 8 8 0 0 0 0 0 8 0 0 15 22 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 15 15 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 22 0 0 50 15 0 0 0 0 % R
% Ser: 0 0 8 29 36 8 0 72 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 8 0 36 0 0 0 0 0 0 0 0 8 % T
% Val: 0 0 0 0 0 0 0 8 43 0 15 0 22 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _