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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RDH11 All Species: 32.12
Human Site: S170 Identified Species: 54.36
UniProt: Q8TC12 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TC12 NP_057110.3 318 35386 S170 K L K E S A P S R I V N V S S
Chimpanzee Pan troglodytes XP_510021 635 69387 S144 K L K E S A P S R I V N V S S
Rhesus Macaque Macaca mulatta XP_001107838 318 35380 S170 K L K E S A P S R I V N V S S
Dog Lupus familis XP_854354 337 37237 S189 K L K E S A P S R I V N V S S
Cat Felis silvestris
Mouse Mus musculus Q9QYF1 316 35129 S167 K L K E S A P S R I V N L S S
Rat Rattus norvegicus NP_001012193 316 35103 S167 K L K E S G P S R V V N V S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521365 217 24366 S75 P G R V V N V S S L A H V I G
Chicken Gallus gallus Q5F389 414 46711 A253 I L R R S S P A R V V V V S S
Frog Xenopus laevis NP_001085680 329 36102 S167 K M K E S G N S R I I N V S S
Zebra Danio Brachydanio rerio Q803A8 412 46303 A250 V L R L S A P A R V V V V S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLU5 409 46492 I252 L F D Y K T R I I V L S S E S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798545 322 35072 S150 K L K A S A P S R I I N V S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42536 405 43844 P223 D L K N S D Y P S K R L I I V
Baker's Yeast Sacchar. cerevisiae Q08651 330 37466 G166 P L L R H C R G R I I S L S S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.3 97.8 81.3 N.A. 84.9 82.6 N.A. 51.2 32.6 46.8 30.1 N.A. 28.1 N.A. N.A. 47.2
Protein Similarity: 100 43.1 99 87.8 N.A. 91.1 91.5 N.A. 59.7 45.8 63.8 45.3 N.A. 46.2 N.A. N.A. 67
P-Site Identity: 100 100 100 100 N.A. 93.3 86.6 N.A. 13.3 53.3 73.3 60 N.A. 6.6 N.A. N.A. 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 33.3 80 86.6 80 N.A. 26.6 N.A. N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. 29.6 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. 44.4 42.1 N.A.
P-Site Identity: N.A. N.A. N.A. 20 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 50 0 15 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 50 0 0 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 0 0 15 0 8 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 8 0 0 0 0 0 0 8 8 58 22 0 8 15 0 % I
% Lys: 58 0 65 0 8 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 8 79 8 8 0 0 0 0 0 8 8 8 15 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 8 0 0 0 0 58 0 0 0 % N
% Pro: 15 0 0 0 0 0 65 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 22 15 0 0 15 0 79 0 8 0 0 0 0 % R
% Ser: 0 0 0 0 79 8 0 65 15 0 0 15 8 79 86 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % T
% Val: 8 0 0 8 8 0 8 0 0 29 58 15 72 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _