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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RDH11 All Species: 18.48
Human Site: S223 Identified Species: 31.28
UniProt: Q8TC12 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TC12 NP_057110.3 318 35386 S223 L A R R L K G S G V T T Y S V
Chimpanzee Pan troglodytes XP_510021 635 69387 G197 L A R R L K G G P R G N E C G
Rhesus Macaque Macaca mulatta XP_001107838 318 35380 S223 L A R R L K G S G V T T Y S V
Dog Lupus familis XP_854354 337 37237 S242 L A R R L K G S G I T A Y S V
Cat Felis silvestris
Mouse Mus musculus Q9QYF1 316 35129 S220 L A K R L K G S G V T T Y S V
Rat Rattus norvegicus NP_001012193 316 35103 S220 L A R R L K G S R V T T Y S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521365 217 24366 V124 R R L Q G T G V T T Y A L H P
Chicken Gallus gallus Q5F389 414 46711 G315 N R R L S P H G V T S N S V H
Frog Xenopus laevis NP_001085680 329 36102 S227 G T K V T A N S L H P G V A E
Zebra Danio Brachydanio rerio Q803A8 412 46303 G312 H R R M S P H G I C C N A L H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLU5 409 46492 G310 A Q R W K Q R G I S V F S L H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798545 322 35072 V209 G T G V T A N V L H P G V V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42536 405 43844 G312 T F A S L Y P G C I A T T G L
Baker's Yeast Sacchar. cerevisiae Q08651 330 37466 P230 V L C L S V H P G L V M N T N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.3 97.8 81.3 N.A. 84.9 82.6 N.A. 51.2 32.6 46.8 30.1 N.A. 28.1 N.A. N.A. 47.2
Protein Similarity: 100 43.1 99 87.8 N.A. 91.1 91.5 N.A. 59.7 45.8 63.8 45.3 N.A. 46.2 N.A. N.A. 67
P-Site Identity: 100 46.6 100 86.6 N.A. 93.3 93.3 N.A. 6.6 6.6 6.6 6.6 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 46.6 100 93.3 N.A. 100 93.3 N.A. 13.3 13.3 20 6.6 N.A. 13.3 N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 29.6 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. 44.4 42.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 43 8 0 0 15 0 0 0 0 8 15 8 8 0 % A
% Cys: 0 0 8 0 0 0 0 0 8 8 8 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 15 0 8 0 8 0 50 36 36 0 8 15 0 8 8 % G
% His: 8 0 0 0 0 0 22 0 0 15 0 0 0 8 22 % H
% Ile: 0 0 0 0 0 0 0 0 15 15 0 0 0 0 0 % I
% Lys: 0 0 15 0 8 43 0 0 0 0 0 0 0 0 8 % K
% Leu: 43 8 8 15 50 0 0 0 15 8 0 0 8 15 8 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 8 0 0 0 0 0 15 0 0 0 0 22 8 0 8 % N
% Pro: 0 0 0 0 0 15 8 8 8 0 15 0 0 0 8 % P
% Gln: 0 8 0 8 0 8 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 22 58 43 0 0 8 0 8 8 0 0 0 0 0 % R
% Ser: 0 0 0 8 22 0 0 43 0 8 8 0 15 36 0 % S
% Thr: 8 15 0 0 15 8 0 0 8 15 36 36 8 8 0 % T
% Val: 8 0 0 15 0 8 0 15 8 29 15 0 15 15 36 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 0 8 0 36 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _