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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ENKUR All Species: 43.64
Human Site: S220 Identified Species: 87.27
UniProt: Q8TC29 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TC29 NP_659447.1 256 29454 S220 S L S V F I D S I P K K I R K
Chimpanzee Pan troglodytes XP_001157277 256 29446 S220 S L S V F I D S I P K K I R K
Rhesus Macaque Macaca mulatta XP_001101074 254 29304 S219 S L S V F I D S I P K K I R K
Dog Lupus familis XP_544232 255 29842 S220 S L S V F I D S I P K K I R K
Cat Felis silvestris
Mouse Mus musculus Q6SP97 255 29509 S220 S L S V F I D S V P K K I R K
Rat Rattus norvegicus NP_001099596 255 29508 S220 S L S V F I D S I P K K I R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506317 255 29078 S220 A L S V V I D S T P K K M R K
Chicken Gallus gallus XP_418600 253 29394 T218 C L S V E I D T I P K K L Y K
Frog Xenopus laevis NP_001088736 265 30674 T230 A L S V V I D T P P K K A H K
Zebra Danio Brachydanio rerio XP_001339781 259 30561 T224 G L S V V I D T A P K K Y R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647729 307 34789 S272 S M S L L I D S I A K R Q R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784094 258 30046 T223 G L S V V T D T A P K K A R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 83.5 87.5 N.A. 87.1 84.7 N.A. 71.4 64 58.4 55.9 N.A. 27.6 N.A. N.A. 53.1
Protein Similarity: 100 99.2 89.4 92.5 N.A. 94.1 91.8 N.A. 86.3 78.9 73.5 72.5 N.A. 44.2 N.A. N.A. 72
P-Site Identity: 100 100 100 100 N.A. 93.3 100 N.A. 73.3 66.6 60 66.6 N.A. 60 N.A. N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 80 73.3 73.3 N.A. 80 N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 0 0 0 0 0 17 9 0 0 17 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 50 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 92 0 0 59 0 0 0 50 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 100 92 0 0 100 % K
% Leu: 0 92 0 9 9 0 0 0 0 0 0 0 9 0 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 9 92 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 9 0 84 0 % R
% Ser: 59 0 100 0 0 0 0 67 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 9 0 34 9 0 0 0 0 0 0 % T
% Val: 0 0 0 92 34 0 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _