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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIWIL2 All Species: 8.18
Human Site: S137 Identified Species: 16.36
UniProt: Q8TC59 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TC59 NP_001129193.1 973 109849 S137 D S K M A E T S V G W S R T L
Chimpanzee Pan troglodytes XP_528083 973 109707 S137 D S K M A E A S V G W S R T L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543251 972 109396 C134 D S K M A E A C V G W N R M L
Cat Felis silvestris
Mouse Mus musculus Q8CDG1 971 109470 S135 D S K L A E A S V G W S R M L
Rat Rattus norvegicus Q4G033 848 95953 A104 S G I P V Q L A T N L F H L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517374 945 106464 V133 L P P G R A T V G L G R A S P
Chicken Gallus gallus A6N7Y9 867 99268 I123 S G A M I K L I A N F F R L T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2CEI6 1046 116189 V210 L T P E R E E V R S E E S I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKM1 843 97159 L99 T D G V P V M L Q T N F F R L
Honey Bee Apis mellifera XP_001120996 812 92430 A68 I N L K L D P A K G L F N Y E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001107667 959 107692 P128 K S P A R Q T P S P A R Q S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SJK3 997 111116 P132 I T S T E T K P E M T S L P P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 N.A. 90.3 N.A. 87.9 34.6 N.A. 71.3 38.6 N.A. 55 N.A. 29.7 32.9 N.A. 41.9
Protein Similarity: 100 99.2 N.A. 93.4 N.A. 93 52.7 N.A. 80.9 57.1 N.A. 69.3 N.A. 49.1 51 N.A. 61
P-Site Identity: 100 93.3 N.A. 73.3 N.A. 80 0 N.A. 6.6 13.3 N.A. 6.6 N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 93.3 N.A. 80 N.A. 86.6 13.3 N.A. 13.3 26.6 N.A. 13.3 N.A. 13.3 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 20.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 34 9 25 17 9 0 9 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 34 9 0 0 0 9 0 0 0 0 0 0 0 0 9 % D
% Glu: 0 0 0 9 9 42 9 0 9 0 9 9 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 34 9 0 0 % F
% Gly: 0 17 9 9 0 0 0 0 9 42 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 17 0 9 0 9 0 0 9 0 0 0 0 0 9 0 % I
% Lys: 9 0 34 9 0 9 9 0 9 0 0 0 0 0 0 % K
% Leu: 17 0 9 9 9 0 17 9 0 9 17 0 9 17 42 % L
% Met: 0 0 0 34 0 0 9 0 0 9 0 0 0 17 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 17 9 9 9 0 0 % N
% Pro: 0 9 25 9 9 0 9 17 0 9 0 0 0 9 25 % P
% Gln: 0 0 0 0 0 17 0 0 9 0 0 0 9 0 0 % Q
% Arg: 0 0 0 0 25 0 0 0 9 0 0 17 42 9 0 % R
% Ser: 17 42 9 0 0 0 0 25 9 9 0 34 9 17 9 % S
% Thr: 9 17 0 9 0 9 25 0 9 9 9 0 0 17 9 % T
% Val: 0 0 0 9 9 9 0 17 34 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _