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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL2
All Species:
14.24
Human Site:
T205
Identified Species:
28.48
UniProt:
Q8TC59
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC59
NP_001129193.1
973
109849
T205
P
D
R
P
L
V
L
T
V
E
H
K
E
K
E
Chimpanzee
Pan troglodytes
XP_528083
973
109707
T205
P
D
R
P
L
V
L
T
V
E
H
K
E
K
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543251
972
109396
A202
L
D
H
S
L
L
G
A
V
E
H
K
E
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDG1
971
109470
T203
A
D
P
P
P
V
L
T
M
E
R
K
E
K
E
Rat
Rattus norvegicus
Q4G033
848
95953
S172
H
K
V
T
E
L
T
S
E
T
Q
R
G
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517374
945
106464
N201
T
S
N
P
L
G
L
N
L
I
K
I
H
C
Q
Chicken
Gallus gallus
A6N7Y9
867
99268
S191
N
K
V
T
E
V
Y
S
K
T
R
N
G
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEI6
1046
116189
V278
G
T
P
P
K
V
E
V
K
I
E
T
V
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
S167
E
Q
E
I
T
V
L
S
G
K
S
K
L
D
I
Honey Bee
Apis mellifera
XP_001120996
812
92430
I136
I
I
N
L
F
T
S
I
H
P
M
D
E
S
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107667
959
107692
S196
D
E
K
M
G
H
L
S
L
Q
G
K
E
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
L200
N
R
N
V
M
K
L
L
V
K
N
Y
K
D
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
N.A.
90.3
N.A.
87.9
34.6
N.A.
71.3
38.6
N.A.
55
N.A.
29.7
32.9
N.A.
41.9
Protein Similarity:
100
99.2
N.A.
93.4
N.A.
93
52.7
N.A.
80.9
57.1
N.A.
69.3
N.A.
49.1
51
N.A.
61
P-Site Identity:
100
100
N.A.
46.6
N.A.
66.6
0
N.A.
20
6.6
N.A.
26.6
N.A.
20
6.6
N.A.
20
P-Site Similarity:
100
100
N.A.
60
N.A.
73.3
26.6
N.A.
33.3
26.6
N.A.
26.6
N.A.
33.3
13.3
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
9
34
0
0
0
0
0
0
0
0
0
9
0
17
9
% D
% Glu:
9
9
9
0
17
0
9
0
9
34
9
0
50
17
34
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
9
9
9
0
9
0
9
0
17
0
0
% G
% His:
9
0
9
0
0
9
0
0
9
0
25
0
9
9
9
% H
% Ile:
9
9
0
9
0
0
0
9
0
17
0
9
0
9
9
% I
% Lys:
0
17
9
0
9
9
0
0
17
17
9
50
9
34
17
% K
% Leu:
9
0
0
9
34
17
59
9
17
0
0
0
9
0
0
% L
% Met:
0
0
0
9
9
0
0
0
9
0
9
0
0
0
0
% M
% Asn:
17
0
25
0
0
0
0
9
0
0
9
9
0
0
0
% N
% Pro:
17
0
17
42
9
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
9
9
0
0
0
9
% Q
% Arg:
0
9
17
0
0
0
0
0
0
0
17
9
0
0
0
% R
% Ser:
0
9
0
9
0
0
9
34
0
0
9
0
0
9
9
% S
% Thr:
9
9
0
17
9
9
9
25
0
17
0
9
0
0
9
% T
% Val:
0
0
17
9
0
50
0
9
34
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _