KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL2
All Species:
18.18
Human Site:
T297
Identified Species:
36.36
UniProt:
Q8TC59
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC59
NP_001129193.1
973
109849
T297
E
L
K
S
Q
R
K
T
D
S
A
E
I
S
I
Chimpanzee
Pan troglodytes
XP_528083
973
109707
T297
E
L
K
S
Q
R
K
T
D
S
A
E
I
S
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543251
972
109396
T297
E
L
K
S
Q
R
K
T
D
G
A
D
I
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDG1
971
109470
T295
E
L
K
S
Q
R
K
T
D
D
A
E
I
S
I
Rat
Rattus norvegicus
Q4G033
848
95953
L263
A
D
V
N
Y
K
V
L
R
N
E
T
V
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517374
945
106464
I292
E
P
S
S
D
L
C
I
P
F
Y
N
V
V
F
Chicken
Gallus gallus
A6N7Y9
867
99268
L282
A
D
V
S
H
K
I
L
R
S
E
T
V
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEI6
1046
116189
T370
H
L
K
A
E
R
K
T
D
N
Q
E
I
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
V258
G
T
E
I
T
H
K
V
M
R
T
E
T
I
Y
Honey Bee
Apis mellifera
XP_001120996
812
92430
T227
A
R
H
R
V
M
R
T
E
T
V
R
D
I
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107667
959
107692
E287
S
V
R
L
F
D
Q
E
T
I
T
I
K
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
G304
S
N
D
Y
V
S
V
G
R
S
F
F
H
T
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
N.A.
90.3
N.A.
87.9
34.6
N.A.
71.3
38.6
N.A.
55
N.A.
29.7
32.9
N.A.
41.9
Protein Similarity:
100
99.2
N.A.
93.4
N.A.
93
52.7
N.A.
80.9
57.1
N.A.
69.3
N.A.
49.1
51
N.A.
61
P-Site Identity:
100
100
N.A.
80
N.A.
93.3
0
N.A.
13.3
13.3
N.A.
60
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
26.6
N.A.
20
26.6
N.A.
80
N.A.
20
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
9
0
0
0
0
0
0
34
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
9
0
9
9
0
0
42
9
0
9
9
9
9
% D
% Glu:
42
0
9
0
9
0
0
9
9
0
17
42
0
0
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
9
9
9
0
0
9
% F
% Gly:
9
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% G
% His:
9
0
9
0
9
9
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
9
0
0
9
9
0
9
0
9
42
25
50
% I
% Lys:
0
0
42
0
0
17
50
0
0
0
0
0
9
0
0
% K
% Leu:
0
42
0
9
0
9
0
17
0
0
0
0
0
17
0
% L
% Met:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
9
% M
% Asn:
0
9
0
9
0
0
0
0
0
17
0
9
0
9
0
% N
% Pro:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
34
0
9
0
0
0
9
0
0
0
0
% Q
% Arg:
0
9
9
9
0
42
9
0
25
9
0
9
0
0
0
% R
% Ser:
17
0
9
50
0
9
0
0
0
34
0
0
0
25
9
% S
% Thr:
0
9
0
0
9
0
0
50
9
9
17
17
9
9
0
% T
% Val:
0
9
17
0
17
0
17
9
0
0
9
0
25
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
9
0
0
0
0
0
9
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _