KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL2
All Species:
17.88
Human Site:
T451
Identified Species:
35.76
UniProt:
Q8TC59
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC59
NP_001129193.1
973
109849
T451
M
S
D
G
K
E
I
T
F
L
E
Y
Y
S
K
Chimpanzee
Pan troglodytes
XP_528083
973
109707
T451
M
S
D
G
K
E
I
T
F
L
E
Y
Y
S
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543251
972
109396
T451
M
S
D
G
K
E
I
T
F
L
E
Y
Y
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDG1
971
109470
T449
M
S
D
G
K
E
I
T
F
L
E
Y
Y
S
K
Rat
Rattus norvegicus
Q4G033
848
95953
L409
P
M
G
R
Q
Q
Q
L
A
R
L
A
D
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517374
945
106464
D438
N
Y
G
I
T
V
K
D
E
E
Q
P
L
L
I
Chicken
Gallus gallus
A6N7Y9
867
99268
G428
E
Q
R
Q
R
E
I
G
K
L
V
D
C
M
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEI6
1046
116189
T524
L
A
D
G
S
V
T
T
F
V
D
Y
Y
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
A404
Q
R
T
D
R
L
R
A
F
N
H
R
L
Q
N
Honey Bee
Apis mellifera
XP_001120996
812
92430
E373
D
V
F
R
H
F
V
E
Q
V
R
S
N
S
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107667
959
107692
F438
S
R
D
E
E
I
S
F
I
D
Y
Y
K
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
T453
Q
A
L
P
A
I
Q
T
G
S
D
T
R
P
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
N.A.
90.3
N.A.
87.9
34.6
N.A.
71.3
38.6
N.A.
55
N.A.
29.7
32.9
N.A.
41.9
Protein Similarity:
100
99.2
N.A.
93.4
N.A.
93
52.7
N.A.
80.9
57.1
N.A.
69.3
N.A.
49.1
51
N.A.
61
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
0
26.6
N.A.
46.6
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
6.6
33.3
N.A.
73.3
N.A.
13.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
9
0
0
9
9
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
0
50
9
0
0
0
9
0
9
17
9
9
9
0
% D
% Glu:
9
0
0
9
9
42
0
9
9
9
34
0
0
0
0
% E
% Phe:
0
0
9
0
0
9
0
9
50
0
0
0
0
0
0
% F
% Gly:
0
0
17
42
0
0
0
9
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
9
0
17
42
0
9
0
0
0
0
0
17
% I
% Lys:
0
0
0
0
34
0
9
0
9
0
0
0
9
9
50
% K
% Leu:
9
0
9
0
0
9
0
9
0
42
9
0
17
9
0
% L
% Met:
34
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
9
0
0
9
0
9
% N
% Pro:
9
0
0
9
0
0
0
0
0
0
0
9
0
9
0
% P
% Gln:
17
9
0
9
9
9
17
0
9
0
9
0
0
9
0
% Q
% Arg:
0
17
9
17
17
0
9
0
0
9
9
9
9
9
0
% R
% Ser:
9
34
0
0
9
0
9
0
0
9
0
9
0
42
9
% S
% Thr:
0
0
9
0
9
0
9
50
0
0
0
9
0
0
0
% T
% Val:
0
9
0
0
0
17
9
0
0
17
9
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
9
50
42
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _