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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL2
All Species:
20.91
Human Site:
Y363
Identified Species:
41.82
UniProt:
Q8TC59
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC59
NP_001129193.1
973
109849
Y363
R
L
Q
I
W
P
G
Y
A
A
S
I
R
R
T
Chimpanzee
Pan troglodytes
XP_528083
973
109707
Y363
R
L
Q
I
W
P
G
Y
A
A
S
I
R
R
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543251
972
109396
Y363
R
L
Q
I
W
P
G
Y
A
A
S
I
R
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDG1
971
109470
Y361
R
L
Q
I
W
P
G
Y
A
A
S
I
R
R
T
Rat
Rattus norvegicus
Q4G033
848
95953
K323
K
P
T
H
A
F
Q
K
R
D
G
S
E
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517374
945
106464
V352
G
L
F
L
L
A
D
V
S
H
K
V
I
R
N
Chicken
Gallus gallus
A6N7Y9
867
99268
R342
N
P
Q
C
T
F
R
R
A
D
G
S
E
I
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEI6
1046
116189
Y436
R
L
Q
V
W
P
G
Y
S
T
S
I
K
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
K318
P
K
S
T
F
S
C
K
G
R
D
I
S
F
V
Honey Bee
Apis mellifera
XP_001120996
812
92430
I287
F
D
K
G
T
D
K
I
S
L
I
N
Y
Y
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107667
959
107692
Y348
K
L
E
I
W
P
G
Y
I
T
A
I
S
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
K367
V
V
T
D
F
I
S
K
F
L
N
I
R
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
N.A.
90.3
N.A.
87.9
34.6
N.A.
71.3
38.6
N.A.
55
N.A.
29.7
32.9
N.A.
41.9
Protein Similarity:
100
99.2
N.A.
93.4
N.A.
93
52.7
N.A.
80.9
57.1
N.A.
69.3
N.A.
49.1
51
N.A.
61
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
13.3
13.3
N.A.
66.6
N.A.
6.6
0
N.A.
46.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
33.3
20
N.A.
86.6
N.A.
13.3
13.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
0
0
42
34
9
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
9
9
0
0
17
9
0
0
9
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
17
0
0
% E
% Phe:
9
0
9
0
17
17
0
0
9
0
0
0
0
9
0
% F
% Gly:
9
0
0
9
0
0
50
0
9
0
17
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
9
0
0
0
9
0
% H
% Ile:
0
0
0
42
0
9
0
9
9
0
9
67
9
9
0
% I
% Lys:
17
9
9
0
0
0
9
25
0
0
9
0
9
0
9
% K
% Leu:
0
59
0
9
9
0
0
0
0
17
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
9
9
0
0
9
% N
% Pro:
9
17
0
0
0
50
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
50
0
0
0
9
0
0
0
0
0
0
9
0
% Q
% Arg:
42
0
0
0
0
0
9
9
9
9
0
0
42
42
0
% R
% Ser:
0
0
9
0
0
9
9
0
25
0
42
17
17
0
9
% S
% Thr:
0
0
17
9
17
0
0
0
0
17
0
0
0
9
50
% T
% Val:
9
9
0
9
0
0
0
9
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
9
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _