KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL2
All Species:
23.94
Human Site:
Y681
Identified Species:
47.88
UniProt:
Q8TC59
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC59
NP_001129193.1
973
109849
Y681
M
G
P
R
D
D
L
Y
G
A
I
K
K
L
C
Chimpanzee
Pan troglodytes
XP_528083
973
109707
Y681
M
A
P
R
D
D
L
Y
G
A
I
K
K
L
C
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543251
972
109396
Y680
M
G
T
R
D
D
L
Y
G
A
I
K
K
L
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDG1
971
109470
Y679
M
G
T
R
D
D
L
Y
G
A
I
K
K
L
C
Rat
Rattus norvegicus
Q4G033
848
95953
T588
G
M
M
L
S
V
A
T
K
I
A
M
Q
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517374
945
106464
Y653
M
G
S
R
D
D
L
Y
G
A
I
K
K
L
C
Chicken
Gallus gallus
A6N7Y9
867
99268
V607
P
Q
T
A
L
A
I
V
T
K
I
A
L
Q
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEI6
1046
116189
Y754
T
G
N
R
D
D
L
Y
S
A
I
K
K
L
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
A583
N
R
S
L
M
S
I
A
T
K
I
A
I
Q
L
Honey Bee
Apis mellifera
XP_001120996
812
92430
K552
K
L
K
S
I
T
E
K
I
A
L
Q
I
N
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107667
959
107692
Y666
P
T
S
R
D
D
R
Y
S
A
F
K
K
L
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
P670
I
V
S
Q
C
C
Q
P
R
Q
V
N
K
L
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
N.A.
90.3
N.A.
87.9
34.6
N.A.
71.3
38.6
N.A.
55
N.A.
29.7
32.9
N.A.
41.9
Protein Similarity:
100
99.2
N.A.
93.4
N.A.
93
52.7
N.A.
80.9
57.1
N.A.
69.3
N.A.
49.1
51
N.A.
61
P-Site Identity:
100
93.3
N.A.
93.3
N.A.
93.3
0
N.A.
93.3
6.6
N.A.
80
N.A.
6.6
13.3
N.A.
60
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
93.3
13.3
N.A.
93.3
13.3
N.A.
80
N.A.
13.3
26.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
9
9
9
0
67
9
17
0
0
0
% A
% Cys:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
67
% C
% Asp:
0
0
0
0
59
59
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
42
0
0
0
0
0
0
42
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
17
0
9
9
67
0
17
0
0
% I
% Lys:
9
0
9
0
0
0
0
9
9
17
0
59
67
0
0
% K
% Leu:
0
9
0
17
9
0
50
0
0
0
9
0
9
67
9
% L
% Met:
42
9
9
0
9
0
0
0
0
0
0
9
0
9
9
% M
% Asn:
9
0
9
0
0
0
0
0
0
0
0
9
0
9
9
% N
% Pro:
17
0
17
0
0
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
9
0
0
9
0
0
9
0
9
9
17
0
% Q
% Arg:
0
9
0
59
0
0
9
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
34
9
9
9
0
0
17
0
0
0
0
0
0
% S
% Thr:
9
9
25
0
0
9
0
9
17
0
0
0
0
0
9
% T
% Val:
0
9
0
0
0
9
0
9
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _