KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIWIL2
All Species:
19.39
Human Site:
Y861
Identified Species:
38.79
UniProt:
Q8TC59
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC59
NP_001129193.1
973
109849
Y861
K
K
I
S
T
N
L
Y
L
A
A
P
Q
N
F
Chimpanzee
Pan troglodytes
XP_528083
973
109707
Y861
K
K
I
S
T
N
L
Y
L
A
A
P
Q
N
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543251
972
109396
Y860
K
K
I
S
T
N
L
Y
L
A
A
T
E
H
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDG1
971
109470
Y859
K
K
I
S
T
N
L
Y
L
A
A
P
D
H
F
Rat
Rattus norvegicus
Q4G033
848
95953
L748
H
T
L
Q
N
P
P
L
G
T
V
V
D
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517374
945
106464
Y833
K
K
I
N
T
N
L
Y
S
A
T
T
E
H
F
Chicken
Gallus gallus
A6N7Y9
867
99268
P767
G
G
L
K
N
P
P
P
G
T
V
V
D
I
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2CEI6
1046
116189
Y934
K
R
I
S
T
T
L
Y
S
Y
G
S
D
H
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKM1
843
97159
P743
L
N
G
Q
N
P
P
P
G
T
I
V
D
D
V
Honey Bee
Apis mellifera
XP_001120996
812
92430
P712
T
G
L
K
N
P
P
P
G
T
I
V
D
S
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001107667
959
107692
F847
K
R
I
N
T
R
I
F
S
V
A
G
G
N
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SJK3
997
111116
N860
L
F
P
E
Q
H
G
N
R
D
M
T
D
K
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
N.A.
90.3
N.A.
87.9
34.6
N.A.
71.3
38.6
N.A.
55
N.A.
29.7
32.9
N.A.
41.9
Protein Similarity:
100
99.2
N.A.
93.4
N.A.
93
52.7
N.A.
80.9
57.1
N.A.
69.3
N.A.
49.1
51
N.A.
61
P-Site Identity:
100
100
N.A.
80
N.A.
86.6
0
N.A.
60
0
N.A.
46.6
N.A.
0
0
N.A.
33.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
13.3
N.A.
80
6.6
N.A.
60
N.A.
6.6
13.3
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
42
42
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
59
9
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
0
0
17
0
17
% E
% Phe:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
50
% F
% Gly:
9
17
9
0
0
0
9
0
34
0
9
9
9
0
0
% G
% His:
9
0
0
0
0
9
0
0
0
0
0
0
0
34
9
% H
% Ile:
0
0
59
0
0
0
9
0
0
0
17
0
0
9
0
% I
% Lys:
59
42
0
17
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
17
0
25
0
0
0
50
9
34
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
9
0
17
34
42
0
9
0
0
0
0
0
25
0
% N
% Pro:
0
0
9
0
0
34
34
25
0
0
0
25
0
0
0
% P
% Gln:
0
0
0
17
9
0
0
0
0
0
0
0
17
0
0
% Q
% Arg:
0
17
0
0
0
9
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
0
42
0
0
0
0
25
0
0
9
0
17
9
% S
% Thr:
9
9
0
0
59
9
0
0
0
34
9
25
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
17
34
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
9
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _