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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C12orf12 All Species: 3.94
Human Site: Y158 Identified Species: 21.67
UniProt: Q8TC90 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TC90 NP_689851.1 406 46482 Y158 R H H P R H S Y P R S P P A D
Chimpanzee Pan troglodytes XP_509258 395 45249 S156 R H H P R R S S P R S P P A D
Rhesus Macaque Macaca mulatta XP_001103978 327 37405 N123 S C W N G S W N P S W A R P P
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9CQL2 403 46194 F157 R R H P R R S F P R N P P I D
Rat Rattus norvegicus Q6AY45 400 45774 F157 R R H P R R S F P R N P P I D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 76.1 N.A. N.A. 62.5 62.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96 77.3 N.A. N.A. 70.4 72.9 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 6.6 N.A. N.A. 66.6 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 6.6 N.A. N.A. 80 80 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 20 0 40 0 % A
% Cys: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 40 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 40 80 0 0 20 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 40 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 20 0 0 0 20 0 0 40 0 0 0 0 % N
% Pro: 0 0 0 80 0 0 0 0 100 0 0 80 80 20 20 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 80 40 0 0 80 60 0 0 0 80 0 0 20 0 0 % R
% Ser: 20 0 0 0 0 20 80 20 0 20 40 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 20 0 0 0 20 0 0 0 20 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _