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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf12
All Species:
11.21
Human Site:
Y251
Identified Species:
61.67
UniProt:
Q8TC90
Number Species:
4
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC90
NP_689851.1
406
46482
Y251
W
G
L
Q
E
T
L
Y
G
F
V
Q
N
P
S
Chimpanzee
Pan troglodytes
XP_509258
395
45249
Y249
W
G
L
Q
E
T
L
Y
G
F
V
Q
N
P
S
Rhesus Macaque
Macaca mulatta
XP_001103978
327
37405
Q210
Q
Q
E
A
L
R
A
Q
K
A
P
V
S
G
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQL2
403
46194
Y249
S
Q
L
P
E
D
L
Y
G
F
M
Q
D
P
S
Rat
Rattus norvegicus
Q6AY45
400
45774
Y249
S
Q
L
P
E
D
L
Y
G
F
M
Q
D
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
76.1
N.A.
N.A.
62.5
62.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96
77.3
N.A.
N.A.
70.4
72.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
N.A.
N.A.
60
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
N.A.
N.A.
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
20
0
0
20
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
40
0
0
0
0
0
0
40
0
0
% D
% Glu:
0
0
20
0
80
0
0
0
0
0
0
0
0
0
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
80
0
0
0
0
0
% F
% Gly:
0
40
0
0
0
0
0
0
80
0
0
0
0
20
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% K
% Leu:
0
0
80
0
20
0
80
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
40
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% N
% Pro:
0
0
0
40
0
0
0
0
0
0
20
0
0
80
0
% P
% Gln:
20
60
0
40
0
0
0
20
0
0
0
80
0
0
0
% Q
% Arg:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% R
% Ser:
40
0
0
0
0
0
0
0
0
0
0
0
20
0
80
% S
% Thr:
0
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
40
20
0
0
0
% V
% Trp:
40
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _