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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL6
All Species:
22.73
Human Site:
S184
Identified Species:
45.45
UniProt:
Q8TCB7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCB7
NP_689609.2
284
33251
S184
K
V
L
K
P
G
K
S
V
L
F
R
D
Y
G
Chimpanzee
Pan troglodytes
XP_001159583
284
33188
S184
K
V
L
K
P
G
K
S
V
L
F
R
D
Y
G
Rhesus Macaque
Macaca mulatta
XP_001082383
284
33277
S184
K
V
L
K
P
G
K
S
V
L
F
R
D
Y
G
Dog
Lupus familis
XP_534257
274
32152
S183
Q
V
L
K
P
G
K
S
V
L
F
R
D
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BVH9
282
32768
S184
K
V
L
K
P
G
R
S
V
L
F
R
D
Y
G
Rat
Rattus norvegicus
Q6AXU8
287
33363
S184
K
V
L
K
P
G
R
S
V
L
F
R
D
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514519
297
34555
C208
K
V
L
K
P
G
K
C
V
L
F
R
D
Y
G
Chicken
Gallus gallus
Q5ZHP8
370
42711
M280
R
L
L
K
P
G
G
M
I
L
L
R
D
Y
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
V264
R
L
L
K
P
G
G
V
L
L
L
R
D
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
L239
R
Y
L
R
P
G
G
L
L
L
F
R
D
Y
G
Honey Bee
Apis mellifera
XP_623532
439
50081
I187
N
V
L
D
K
G
G
I
V
L
F
R
D
Y
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794407
277
31720
L187
K
A
L
C
P
G
G
L
V
L
F
R
D
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
94.3
89.7
N.A.
85.5
84.3
N.A.
77.7
37
N.A.
36.8
N.A.
38.1
32.3
N.A.
59.5
Protein Similarity:
100
99.6
97.1
94
N.A.
91.9
90.9
N.A.
85.1
49.7
N.A.
50.4
N.A.
51.3
46.4
N.A.
73.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
60
N.A.
60
N.A.
60
66.6
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
80
N.A.
80
N.A.
80
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
0
100
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
84
0
0
0
0
% F
% Gly:
0
0
0
0
0
100
42
0
0
0
0
0
0
0
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% I
% Lys:
59
0
0
75
9
0
42
0
0
0
0
0
0
0
0
% K
% Leu:
0
17
100
0
0
0
0
17
17
100
17
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
92
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
25
0
0
9
0
0
17
0
0
0
0
100
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
67
0
0
0
0
0
9
75
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
100
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _