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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METTL6 All Species: 36.36
Human Site: T63 Identified Species: 72.73
UniProt: Q8TCB7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCB7 NP_689609.2 284 33251 T63 F F K D R H W T T R E F E E L
Chimpanzee Pan troglodytes XP_001159583 284 33188 T63 F F K D R H W T T R E F E E L
Rhesus Macaque Macaca mulatta XP_001082383 284 33277 T63 F F K D R H W T T R E F E E L
Dog Lupus familis XP_534257 274 32152 T63 F F K D R H W T T R E F E D L
Cat Felis silvestris
Mouse Mus musculus Q8BVH9 282 32768 T63 F F K D R H W T T R E F E E L
Rat Rattus norvegicus Q6AXU8 287 33363 T63 F F K D R H W T T R E F E E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514519 297 34555 T87 F F K D R H W T T R E F E E L
Chicken Gallus gallus Q5ZHP8 370 42711 L90 F F K D R H W L F T E F P E L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A8KBL7 353 40469 L111 F F K D R H W L F T E F P E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q86BS6 325 38113 L114 F F K D R H W L F T E F P E L
Honey Bee Apis mellifera XP_623532 439 50081 T67 F F K D R H W T T R E F D E L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794407 277 31720 T68 F F K D R H W T T R E F E E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 94.3 89.7 N.A. 85.5 84.3 N.A. 77.7 37 N.A. 36.8 N.A. 38.1 32.3 N.A. 59.5
Protein Similarity: 100 99.6 97.1 94 N.A. 91.9 90.9 N.A. 85.1 49.7 N.A. 50.4 N.A. 51.3 46.4 N.A. 73.2
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 100 73.3 N.A. 73.3 N.A. 73.3 93.3 N.A. 100
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 73.3 N.A. 73.3 N.A. 73.3 100 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 100 0 0 0 0 0 0 0 0 9 9 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 100 0 67 92 0 % E
% Phe: 100 100 0 0 0 0 0 0 25 0 0 100 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 25 0 0 0 0 0 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 100 0 0 0 0 75 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 75 75 25 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _